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Data from: An experimental analysis of the molecular effects of trastuzumab (herceptin) and fulvestrant (falsodex), as single agents
- 负责人:
- DOI:
- doi:10.5061/dryad.7mp37
- 摘要:
- liferation and cell cycle progression or in an increased rate of apoptosis were studied. The distribution and abundance of the proteins p-Akt and p-Erk expressed in these cell
Data from: Recruitment of Pontin/Reptin by E2f1 amplifies E2f transcriptional response during cancer progression
- 负责人:
- 关键词:
- E2F
- DOI:
- doi:10.5061/dryad.31q7p
- 摘要:
- , following inactivation of the Rb gene family in a mouse model of liver cancer, initially activates a robust gene expression program associated with the cell cycle. Slowly
Data from: Aberrant FGFR signaling mediates resistance to CDK4/6 inhibitors in ER+ breast cancer
- 负责人:
- 关键词:
- USA;Breast Cancer
- DOI:
- doi:10.5061/dryad.20j465p
- 摘要:
- progression-free survival compared to patients with wild type FGFR1. Thus, we propose breast cancers with FGFR pathway alterations should be considered for trials usi
Data from: Comparative analysis of ear-hole closure identifies epimorphic regeneration as a discrete trait in mammals
- 负责人:
- 关键词:
- DOI:
- doi:10.5061/dryad.1q7j5
- 摘要:
- reveal that injury induces blastema formation in Acomys cahirinus. Despite cell cycle re-entry in Mus musculus and A. cahirinus, efficient cell cycle progression and pro
Data from: The translational landscape of the splicing factor SRSF1 and its role in mitosis
- 负责人:
- 关键词:
- Homo Sapiens
- DOI:
- doi:10.5061/dryad.5sv39
- 摘要:
- gation. Indeed, we show that translational activity of SRSF1 is required for normal mitotic progression. Furthermore, we found that mRNAs that display
Data from: Paradoxical aortic stiffening and subsequent cardiac dysfunction in Hutchinson–Gilford progeria syndrome
- 负责人:
- DOI:
- doi:10.5061/dryad.mcvdncjw9
- 摘要:
- , only to succumb progressively to pressure-related effects of the lamin A mutation and become extreme in the peri-morbid period. Because the dramatic life
Data from: A study of the transit amplification divisions during spermatogenesis in Oncopeltus fasciatus to assess plasticity in sperm number
- 负责人:
- DOI:
- doi:10.5061/dryad.q57n9h7
- 摘要:
- on how nutrition affects male fertility in insects. We further examined the mechanisms by which sperm are produced by examining the progression
Data from: Predicting bioprocess targets of chemical compounds through integration of chemical-genetic and genetic interactions
- 负责人:
- 关键词:
- DOI:
- doi:10.5061/dryad.nr2cf12
- 摘要:
- s of these predictions. We also present experimental validations of CG-TARGET-predicted tubulin polymerization and cell cycle progression inhibitors
IPCC Climate Change Data: HADCM3 A1F Model: 2050 Precipitation
- 负责人:
- DOI:
- doi:10.5063/aa/dpennington.187.2
- 摘要:
- up A1FI, emissions approach those of the A2 scenarios; conversely in scenario group A1T with low labor productivity or of rapid progress in "post-fossi
IPCC Climate Change Data: HADCM3 A1F Model: 2050 Minimum Temperature
- 负责人:
- DOI:
- doi:10.5063/aa/dpennington.193.2
- 摘要:
- up A1FI, emissions approach those of the A2 scenarios; conversely in scenario group A1T with low labor productivity or of rapid progress in "post-fossi