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Data from: Leptin regulation of hippocampal synaptic function in health and disease
负责人:
关键词:
AMPA receptor trafficking;GluA1;Leptin
DOI:
doi:10.5061/dryad.n8f46
摘要:
The endocrine hormone leptin plays a key role in regulating food intake and body weight via its actions in the hypothalamus. However, leptin receptors
Data from: Biophysically inspired model for functionalized nanocarrier adhesion to cell surface: roles of protein expression and mechanical factors
负责人:
关键词:
tissue targeting;cell membrane;entropy loss upon binding;functionalized nanocarriers;pharmacodynamic model;free energy landscape
DOI:
doi:10.5061/dryad.4h76d
摘要:
density, receptor expression, bending mechanics of the target cell membrane, as well as entropic factors associated with the membrane and the receptor motion
on their affinity for the aryl hydrocarbon receptor.
负责人:
关键词:
Hepatocytes;polycyclic aromatic hydrocarbons;exosome;cell death;Extracellular vesicles;aryl hydrocarbon receptor
DOI:
doi:10.5061/dryad.3n39r6k
摘要:
r affinity for the aryl hydrocarbon receptor (AhR): benzo(a)pyrene (BP), dibenzo(a,h)anthracene (DBA), and pyrene (PYR). Treatment of primary rat and WIF-B9
Data from: Repurposed transcriptomic data facilitate discovery of innate immunity Toll-Like Receptor (TLR) genes across Lophotrochozoa
负责人:
关键词:
Toll TLR Toll-like receptor data mining
DOI:
doi:10.5061/dryad.0318j
摘要:
ted to a transmembrane domain and an intracellular toll/interleukin-1 receptor (TIR) domain. Consequently, these genes are important in initiating a signaling pathway to trigger
Data from: Dopamine promotes motor cortex plasticity and motor skill learning via PLC activation
负责人:
关键词:
phospholipase C;long term potentiation;motor cortex;learning;synaptic plasticity;dopamine
DOI:
doi:10.5061/dryad.mp5s3
摘要:
skill learning and motor cortex synaptic plasticity. Dopamine D1 and D2 receptor antagonists exert parallel effects in the motor system: they impair motor skill learning and reduce
Data from: Down-regulation of CXCL12/CXCR4 expression alleviates ischemia-reperfusion-induced inflammatory pain via inhibiting glial TLR4 activation
负责人:
关键词:
DOI:
doi:10.5061/dryad.5934k
摘要:
Toll-like receptor 4 (TLR4) is important for the pathogenesis of inflammatory reactions and the promotion of pain processing after ischemia
Data from: Loss of olfaction in sea snakes provides new perspectives on the aquatic adaptation of amniotes
负责人:
关键词:
OR;Hydrophis melanocephalus;Laticauda colubrina;amphibious;Vipera berus;Anolis carolinensis;Thamnophis sirtalis;terrestrial;fully aquatic;V1R;V2R;Emydocephalus ijimae;TAAR;Laticauda laticaudata;Ophiophagus hannah
DOI:
doi:10.5061/dryad.t8sm4m6
摘要:
of fully-aquatic and amphibious sea snakes, and identified repertoires of chemosensory receptor genes involved in olfaction. Snakes possess large numb
Data from: Regulation of Somatostatin receptor 2 trafficking by C-tail motifs and the retromer
负责人:
关键词:
SNX1\/2;Rab proteins;retromer;Somatostatin receptor 2;PDZ domain;trafficking
DOI:
doi:10.5061/dryad.2h9d7sh
摘要:
The Gi-coupled somatostatin receptor 2 (SST2) is a G-protein coupled receptor (GPCR) that mediates many of somatostatin’s neuroendocrine actions
Data from: Intracellular glucocorticoid receptors in spleen, but not skin, vary seasonally in wild house sparrows (Passer domesticus)
负责人:
Lattin, Christine R.
关键词:
DOI:
doi:10.5061/dryad.6mb78
摘要:
seasonal patterns in both circulating CORT and immune function across many animal species, but whether CORT receptor density in immune tissues varies seasonally is cu
Data from: Wnt/PCP controls spreading of Wnt/?-catenin signals by cytonemes in vertebrates
负责人:
关键词:
n\/a;Cytoneme;Danio rerio
DOI:
doi:10.5061/dryad.38q5pc1
摘要:
, the receptor tyrosine kinase Ror2 gets activated. Ror2/PCP signaling leads to induction of cytonemes, which mediate transport of Wnt8a to neighboring cells. In the Wnt rece

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