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Human Lim Domain Kinase 1 (Limk1), Kinase Domain; A Target Enabling Package
- 负责人：
- 关键词：
- protein target enabling package disease structure cancer neuropsychiatry neuro neurological genetic disorders metabolic diseases oncology
- DOI：
- doi:10.5281/zenodo.1287260
- 摘要：
- that may potentially allow the development of a safe drug for this chronic indication.;;This document represents version 4 of the TEP datasheet
Human Lim Domain Kinase 1 (Limk1), Kinase Domain; A Target Enabling Package
- 负责人：
- 关键词：
- protein target enabling package disease structure cancer neuropsychiatry neuro neurological genetic disorders metabolic diseases oncology
- DOI：
- doi:10.5281/zenodo.1241027
- 摘要：
- that may potentially allow the development of a safe drug for this chronic indication.;;This document represents version 3 of the TEP datasheet
Human LIM domain kinase 1 (LIMK1), kinase domain; A Target Enabling Package
- 负责人：
- 关键词：
- protein target enabling package disease structure cancer neuropsychiatry neuro neurological genetic disorders metabolic diseases oncology
- DOI：
- doi:10.5281/zenodo.1219706
- 摘要：
- that may potentially allow the development of a safe drug for this chronic indication.;;This document represents version 6 of the TEP datasheet
\u2022\tRegulatory requirement for drug development and approval in United States: review
- 负责人：
- 关键词：
- 111701 Aboriginal and Torres Strait Islander Health 111001 Aged Care Nursing 111702 Aged Health Care 110301 Anaesthesiology 110901 Autonomic Nervous System 111501 Basic Pharmacology Biomarkers 110601 Biomechanics 111201 Cancer Cell Biology 111202 Cancer Diagnosis
- DOI：
- doi:10.6084/m9.figshare.3381274.v1
- 摘要：
- the effectiveness and safety of the drug product. In the United States, however, no regulations were put forth until the Pure Food and Drug Act was passed
Data from: Development and evaluation of a fluorescent antibody-drug conjugate for molecular imaging and targeted therapy of pancreatic cancer
- 负责人：
- DOI：
- doi:10.5061/dryad.6j018
- 摘要：
- safety and efficacy of such biologics, these techniques can also be difficult, expensive, and time-consuming. Furthermore, antibody-drug conjugates (ADCs
Data to Support Efficacy Studies of Injectable Tulathromycin for Reduction of Vertical Transmission of Renibacterium salmoninarum in Spring
- 负责人：
- 关键词：
- DOI：
- doi:10.5066/p90vqu3q
- 摘要：
- males and (3) improved fish husbandry. However, the future availability of the injectable macrolide antibiotic (erythromycin) used for adults is uncertain. This drug
Data from: Medical-device recalls in the UK and the device-regulation process: retrospective review of safety notices and alerts
- 负责人：
- DOI：
- doi:10.5061/dryad.585t4
- 摘要：
- , and Food and Drug Administration recall system of severity. Results: In total, 2124 field safety notices were issued over the 5-year period, an increase of 1220% (62 in 2006
Data from: A novel open access web portal for integrating mechanistic and toxicogenomic study results
- 负责人：
- DOI：
- doi:10.5061/dryad.159h65k
- 摘要：
- Applying toxicogenomics to improving the safety profile of drug candidates and crop protection molecules is most useful when it identifies relevant
Data from: Efficacy and safety of four weeks’ treatment with combined fluticasone furoate/vilanterol in a single inhaler given once daily in COPD
- 负责人：
- DOI：
- doi:10.5061/dryad.7p1r30q5
- 摘要：
- e to assess the safety and efficacy of FF/VI 400/25 ?g OD administered for 4 weeks via a novel dry powder inhaler. Co-primary end points were change from
Data from: Increased dystrophin production with golodirsen in patients with Duchenne muscular dystrophy
- 负责人：
- DOI：
- doi:10.5061/dryad.g003051
- 摘要：
- patients. Most of the study drug was excreted within 4 hours following administration. A significant increase in exon 53 skipping was associated with ~16
