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Data from: Genome editing in butterflies reveals that spalt promotes and Distal-less represses eyespot colour patterns
- 负责人：
- DOI：
- doi:10.5061/dryad.tj45p
- 摘要：
- ing genes. Little is known, however, about how, or even whether, co-opted genes function in eyespot development. Here we use CRISPR/Cas9 genome editing
Data from: Genome-wide CRISPR synthetic lethality screen identifies a role for the ADP-ribosyltransferase PARP14 in replication fork
- 负责人：
- 关键词：
- dna damage response
- DOI：
- doi:10.5061/dryad.p8cz8w9mj
- 摘要：
- tic components that impact cellular viability upon loss of PARP14 by performing an unbiased, comprehensive, genome-wide CRISPR knockout genetic screen in PARP14
Data from: CRISPR-based herd immunity limits phage epidemics in bacterial populations
- 负责人：
- DOI：
- doi:10.5061/dryad.42n44
- 摘要：
- frequencies of susceptible and resistant cells harboring CRISPR immunity. In addition, we develop a mathematical model that quantifies how herd immunity
Data from: The complete genome sequence of the thermophilic bacterium Laceyella sacchari FBKL4.010 reveals the basis for tetramethylpyrazine biosynthesis in Moutai?flavor Daqu
- 负责人：
- DOI：
- doi:10.5061/dryad.82gn3m6
- 摘要：
- chromosome with 3,145 coding sequences (CDSs), seven clustered regularly interspaced short palindromic repeat (CRISPR) regions of 12 CRISPRs. Moreove
Data from: Evolutionary trade-offs of insecticide resistance – the fitness costs associated with target-site mutations in the nAChR of Drosophila melanogaster
- 负责人：
- DOI：
- doi:10.5061/dryad.v9s4mw6sc
- 摘要：
- and to test whether it may confer any significant fitness costs to insects, CRISPR/Cas9 was used to introduce an analogous mutation in the genome
Data from: Whole organism lineage tracing by combinatorial and cumulative genome editing
- 负责人：
- DOI：
- doi:10.5061/dryad.478t9
- 摘要：
- . The barcode, an array of clustered regularly interspaced short palindromic repeats (CRISPR)/Cas9 target sites, marks cells and enables the elucidation
Data from: Identification of a transporter complex responsible for the cytosolic entry of nitrogen-containing-bisphosphonates
- 负责人：
- DOI：
- doi:10.5061/dryad.p6261d6
- 摘要：
- ace to reach their molecular target is not understood. Here we implemented a CRISPRi-mediated genome-wide screen and identified SLC37A3 (solute carrier family 37
Data from: Tethered homing gene drives: a new design for spatially restricted population replacement and suppression
- 负责人：
- DOI：
- doi:10.5061/dryad.70dn712
- 摘要：
- of unintended spread of engineered organisms beyond the target population. In response, several novel gene drive approaches have been proposed that can, under cer
Data from: Reprogramming the antigen specificity of B cells using genome-editing technologies
- 负责人：
- DOI：
- doi:10.5061/dryad.45j0r70
- 摘要：
- B cells directly using genome editing technologies. We used CRISPR-Cas9 in a homology directed repair strategy, to replace the heavy chain (HC
Data from: Self-limiting population genetic control with sex-linked genome editors
- 负责人：
- DOI：
- doi:10.5061/dryad.474j412
- 摘要：
- In male heterogametic species the Y chromosome is transmitted solely from fathers to sons, and is selected for based only on its impacts
