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Data from: A RhoG-mediated signaling pathway that modulates invadopodia dynamics in breast cancer cells
负责人:
关键词:
guanine nucleotide-exchange factor;guanine-nucleotide exchange factors;invadopodia;Rho GTPases;SGEF;cytoskeleton;RhoG;Cell Migration;paxillin;Breast Cancer;cell invasion;rac1
DOI:
doi:10.5061/dryad.q1j50
摘要:
of invadopodia disassembly in human breast cancer cells. Our results show that RhoG and Rac1 have independent and opposite roles in the regulation of invadopodia
Data from: Quantifying patient preferences for symptomatic breast clinic referral: a decision analysis study
负责人:
关键词:
oncology;Quality in health care;Epidemiology
DOI:
doi:10.5061/dryad.k15f3t5
摘要:
(university) education (n=32, 91.4%) and with knowledge of someone with breast cancer (n=30, 85.7%). When individual preferences were accounted for, 25 (71
Data from: Whole transcriptome RNA-Seq analysis of breast cancer recurrence risk using formalin-fixed paraffin-embedded tumor tissue
负责人:
关键词:
RNA-seq;Next Generation Sequencing;transcriptome;Breast Cancer;Homo Sapiens
DOI:
doi:10.5061/dryad.q760h
摘要:
for biomarker discovery. More than two thousand RNAs are strongly associated with breast cancer recurrence risk in the 136 patient cohort (FDR < 10%). Many of these ar
Data from: A clinical decision support system learned from data to personalize treatment recommendations towards preventing breast cancer metastasis
负责人:
关键词:
treatment;clinical;metastasis;Decision Support;Bayesian network;Breast Cancer;electronic health records;Holocene;EHR;H. sapiens
DOI:
doi:10.5061/dryad.64964m0
摘要:
ecommendations Concerning Breast Cancer Patients (DPAC), which is a CDSS learned from data that recommends the optimal treatment decisions based on a patient’s fea
Data from: Aberrant FGFR signaling mediates resistance to CDK4/6 inhibitors in ER+ breast cancer
负责人:
关键词:
USA;Breast Cancer
DOI:
doi:10.5061/dryad.20j465p
摘要:
of drug resistance. FGFR1-amplified/ER+ breast cancer cells and MCF-7 cells transduced with FGFR1 were resistant to fulvestrant ± ribociclib or palbociclib
Data from: Quantification of sensitivity and resistance of breast cancer cell lines to anti-cancer drugs using GR metrics
负责人:
关键词:
drug response;Breast Cancer;Homo Sapiens
DOI:
doi:10.5061/dryad.03n60
摘要:
, proliferation-corrected, drug sensitivity metrics for ~4,700 pairs of breast cancer cell lines and perturbagens. Such data are broadly useful in under
Data from: Mannose glycosylation is an integral step for human NIS localization and function in breast cancer cells
负责人:
关键词:
Breast Cancer;Sodium Iodide Symporter (NIS);mannose glycosylation;Mannosidase
DOI:
doi:10.5061/dryad.r7sqv9s7f
摘要:
nario of breast cancer (BC), this study addresses key molecular defects involved. Human NIS expression is primarily recorded as a cytoplasmic protein, thus limiting
Data from: The lncRNA H19 mediates breast cancer cell plasticity during EMT and MET plasticity by differentially sponging miR-200b/c and let-7b
负责人:
关键词:
DOI:
doi:10.5061/dryad.t5pv8
摘要:
transition (MET). Using a mouse model of spontaneous metastatic breast cancer, we investigated the molecular mediators of metastatic competence
Data from: Canine mammary tumours are affected by frequent copy number aberrations, including amplification of MYC and loss of PTEN
负责人:
关键词:
DOI:
doi:10.5061/dryad.7dm4d
摘要:
lusions: The high frequency of copy number aberrations is a prominent feature of canine mammary tumours as seen in other canine and human cancers. Our findings share sever
Data from: Clonal relatedness between lobular carcinoma in situ and synchronous malignant lesions
负责人:
关键词:
DOI:
doi:10.5061/dryad.6354b
摘要:
INTRODUCTION: Lobular carcinoma in situ (LCIS) has been accepted as a marker of risk for the development of invasive breast cancer, yet modern models

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