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Data from: Mapping the fitness landscape of gene expression uncovers the cause of antagonism and sign epistasis between adaptive mutations
- 负责人：
- 关键词：
- Experimental evolution;epistasis;Adaptation;fitness landscape;Metabolism;Methylobacterium extorquens
- DOI：
- doi:10.5061/dryad.8hb23
- 摘要：
- ny genes at once? Here we combined independently-arising beneficial mutations that altered enzyme levels in the central meta
Data from: Shifting fitness landscapes in response to altered environments
- 负责人：
- DOI：
- doi:10.5061/dryad.nb259
- 摘要：
- elevated salinity, we observe numerous beneficial mutations with growth advantages up to 7% relative to the wild type. All of these beneficial mutations wer
Data from: Environment changes epistasis to alter trade-offs along alternative evolutionary paths
- 负责人：
- DOI：
- doi:10.5061/dryad.70843h1
- 摘要：
- coevolved mutations in eight diverse environments. We find that mutations are, on average, beneficial across environments, but that there is high variation
Data from: Known mutator alleles do not markedly increase mutation rate in clinical Saccharomyces cerevisiae strains
- 负责人：
- DOI：
- doi:10.5061/dryad.125p3
- 摘要：
- t in asexual populations, mutator alleles, which cause high mutation rates, can fix due to linkage with beneficial mutations. This phenomenon has been demonstrated
Data from: Inferring the age of a fixed beneficial allele
- 负责人：
- 关键词：
- Population Genetics - Theoretical;Ecological Genetics;Adaptation;Population Genetics - Empirical
- DOI：
- doi:10.5061/dryad.qb6b5
- 摘要：
- ons. Several haplotype-based estimators exist for inferring the age of segregating beneficial mutations. Here, we develop an approximate Bayesian based
Data from: Tempo and mode of genome evolution in a 50,000-generation experiment
- 负责人：
- DOI：
- doi:10.5061/dryad.6226d
- 摘要：
- r 50,000 generations. The populations that retained the ancestral mutation rate support a model in which most fixed mutations are beneficial
Data from: Adaptation, clonal interference, and frequency-dependent interactions in a long-term evolution experiment with Escherichia coli
- 负责人：
- DOI：
- doi:10.5061/dryad.3m00k
- 摘要：
- ow strong evidence of selective sweeps as well as clonal interference between competing lineages bearing different beneficial mutations. In some cases, sets
Data from: Effects of beneficial mutations in pykF gene vary over time and across replicate populations in a long-term experiment with bacteria
- 负责人：
- DOI：
- doi:10.5061/dryad.7ck38
- 摘要：
- nce of genetic context in determining the fitness effects of different beneficial mutations even within the same gene.
Data from: Adaptive walks and distribution of beneficial fitness effects
- 负责人：
- 关键词：
- DOI：
- doi:10.5061/dryad.4p502
- 摘要：
- on-weak mutation regime in which beneficial mutations fix sequentially, and the population performs an uphill walk on the fitness landscape until a local
Data from: Epigenetic mutations can both help and hinder adaptive evolution
- 负责人：
- DOI：
- doi:10.5061/dryad.68b3g
- 摘要：
- of beneficial mutations move a population towards a fitness optimum. We use an individual-based model of an asexual population, where mutational effects are drawn from
