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Data from: Consistency of VDJ rearrangement and substitution parameters enables accurate B cell receptor sequence annotation
负责人:
关键词:
B cell maturation;antibody;immunoglobulin;hidden Markov model
DOI:
doi:10.5061/dryad.149m8
摘要:
of antigens. It is now possible to sequence these BCRs in high throughput; analysis of these sequences is bringing new insight into how antibodies develop
Data from: Frequent and seasonally variable sublethal anthrax infections are accompanied by short-lived immunity in an endemic system
负责人:
关键词:
antibody persistence bacteria ecological immunology ELISA endoparasites host-parasite interactions microbiology microparasites seroconversion dynamics serology
DOI:
doi:10.5061/dryad.73f23
摘要:
and longitudinal comparisons. We used enzyme-linked immunosorbent assays to measure anti-anthrax antibody titers and developed three increasingly conservative mod
Data from: Identification and mapping of linear antibody epitopes in human serum albumin using high-density peptide arrays
负责人:
关键词:
B cell epitopes;peptide microarrays;linear epitopes;peptides;human serum albumin
DOI:
doi:10.5061/dryad.3003f
摘要:
antibody preparation. To allow for identification of even the weakest epitopes and at the same time perform a detailed characterization of key residues involved
ng antibody-dependent enhancement
负责人:
Schmid, Michael A.
关键词:
Dengue virus pathogenesis immune response dendritic cells mosquito saliva mouse model endothelial cells antibody-dependent enhancement flow cytometry
DOI:
doi:10.5061/dryad.4rd14
摘要:
specifically in the presence of enhancing serotype-cross-reactive antibodies—when individuals already carry an increased risk for severe disease
Data from: B cell receptor and Toll-like receptor signaling coordinate to control distinct B-1 responses to both self and the microbiota
负责人:
关键词:
spleen;B-1a cells;Peritoneal Cavity;IgH Repertoire;IgM
DOI:
doi:10.5061/dryad.660js04
摘要:
aneously secreted serum antibodies predominately reactive to self antigens, like phosphatidylcholine (PtC), or to the intestinal microbiota. The mechanisms tha
Data from: Long antibody persistence and transgenerational transfer of immunity in a long-lived vertebrate
负责人:
关键词:
Ecology: evolutionary;Life history: evolution;Immunity: ecology;2008-2013;Evolution: host\/parasite;bird;Life history: ecology;Immunity: evolution;Epidemiology;Life history: trade offs;Calonectris borealis
DOI:
doi:10.5061/dryad.rt214
摘要:
—and whether maternal antibodies against that antigen could persist over a long period in offspring several years after the mother was exposed. We found tha
Data from: Antibody responses to Plasmodium vivax Duffy binding and erythrocyte binding proteins predict risk of infection and are associated with
负责人:
关键词:
Plasmodium vivax;PvDBP;PvEBPII;2006-2007;binding inhibitory antibody;IgG antibody responses;protection;malaria
DOI:
doi:10.5061/dryad.n14p52b
摘要:
onal receptor-binding region II of PvDBP (PvDBPII) is highly polymorphic. The natural acquisition of antibodies to different variants of PvDBPII, including
Data from: Reprogramming the antigen specificity of B cells using genome-editing technologies
负责人:
关键词:
HIV broadly neutralizing antibodies;PG9;HIV vaccine;HIV bnAbs genome editing;B cells;antibody repertoire
DOI:
doi:10.5061/dryad.45j0r70
摘要:
We have developed a method to introduce novel paratopes into the human antibody repertoire by modifying the immunoglobulin (Ig) genes of mature
Data from: Naturally acquired antibody responses to more than 300 Plasmodium vivax proteins in three geographic regions
负责人:
关键词:
DOI:
doi:10.5061/dryad.qc7n5
摘要:
. The majority of sero-reactive antigens in all sites induced short-lived antibody responses with estimated half-lives of less than 6 months, although ther
Data from: Identification of novel, clinically correlated autoantigens in the monogenic autoimmune syndrome APS1 by PhIP-Seq
负责人:
关键词:
DOI:
doi:10.7272/Q66H4FM2
摘要:
responses to multiple organs. Importantly, autoantibody discovery in APS1 can illuminate fundamental disease pathogenesis, and many of the antigens found in APS1 extend

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