Data from: High throughput functional genomics identifies modulators of TCE metabolite genotoxicity and candidate susceptibility genes

负责人：

关键词：

trichloroethylene;toxicogenomics;DNA damage and repair mechanisms;susceptibility genes;high-throughput testing;Saccharomyces cerevisiae

DOI：

doi:10.5061/dryad.p8k18

摘要：

Trichloroethylene (TCE), an industrial chemical and environmental contaminant, is a human carcinogen. Reactive metabolites are implicated in renal

Data from: In vivo assessment of respiratory burst inhibition by xenobiotic exposure using larval zebrafish

负责人：

关键词：

Zebrafish;reactive oxygen species (ROS);phagocytes;neutrophil;macrophage;polycyclic aromatic hydrocarbons;Endocrine disrupting chemicals;Acenaphthenequinone;Azathioprine;Benzoapyrene;dexamethasone;Dichloroacetic Acid;17-?-Estradiol;Hydroquinone;Lead acetate (II) trihydrate;Methoxychlor;Phenanthrene;Tributlytin Oxide;trichloroethylene;zebrafish embryo;larval zebrafish;Flow cytometry

DOI：

doi:10.5061/dryad.z8w9ghx86

摘要：

was found to be the only chemical that induced a change in the number of immune cells by increasing macrophage but not neutrophil numbers. Taken together, this work demonstrates

Data from: Genome-scale characterization of toxicity-induced metabolic alterations in primary hepatocytes

负责人：

关键词：

DOI：

doi:10.5061/dryad.04vk390

摘要：

dibenzodioxin, and trichloroethylene) for six hours. TIMBR predictions were compared with paired fresh and spent media metabolomics data from the same exposure conditions. Agreement bet