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Data from: The roles of compensatory evolution and constraint in aminoacyl tRNA synthetase evolution
负责人:
关键词:
DOI:
doi:10.5061/dryad.4p24g
摘要:
aminoacyl tRNA synthetase proteins (mt-aaRS) encoded by the nuclear genome. It has been argued that animal mt-tRNAs have higher deleterious substitution rates
Data from: Metabolite profile of a mouse model of Charcot-Marie-Tooth type 2D neuropathy: implications for disease mechanisms and interventions
负责人:
Burgess, Robert W.
关键词:
Peripheral neuropathy Spinal cord Sciatic nerve Metabolomics Mass Spectrometry tRNA synthetase
DOI:
doi:10.5061/dryad.ng07t
摘要:
in the peripheral nervous system. Charcot-Marie-Tooth type 2D neuropathy (CMT2D) is caused by dominant mutations in glycyl tRNA synthetase (GARS). Mutations in the mouse Gars

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