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Data from: The evolutionary consequences of blood-stage vaccination on the rodent malaria Plasmodium chabaudi
- 负责人:
- DOI:
- doi:10.5061/dryad.h44t1
- 摘要:
- Malaria vaccine developers are concerned that antigenic escape will erode vaccine efficacy. Evolutionary theorists have raised the possibility tha
![](http://agri.nais.net.cn/resources/front/images/source_91.jpg)
Data from: The fitness of drug-resistant malaria parasites in a rodent model: multiplicity of infection
- 负责人:
- DOI:
- doi:10.5061/dryad.853nh
- 摘要:
- asites can have profound effects on the evolution of drug resistance. Here, using the Plasmodium chabaudi mouse malaria model, we ask whether
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Data from: Chemotherapy, within-host ecology and the fitness of drug-resistant malaria parasites
- 负责人:
- DOI:
- doi:10.5061/dryad.4h0g0
- 摘要:
- competitive release. Using the rodent malaria model Plasmodium chabaudi, we found that low-dose chemotherapy did reduce competitive release. A higher drug dose regimen
![](http://agri.nais.net.cn/resources/front/images/source_91.jpg)
Data from: Understanding genetic variation in in vivo tolerance to artesunate: implications for treatment efficacy and resistance monitoring
- 负责人:
- DOI:
- doi:10.5061/dryad.v244v
- 摘要:
- ded to identify a meaningful increase in infection half-life. Here, we show that five previously unexposed genotypes of the rodent malaria par
![](http://agri.nais.net.cn/resources/front/images/source_91.jpg)
Data from: Costs of crowding for the transmission potential in malaria parasites
- 负责人:
- DOI:
- doi:10.5061/dryad.44jf2
- 摘要:
- ensity of rodent malaria (Plasmodium berghei) infections in Anopheles stephensi mosquitoes under different environmental conditions, we show that parasites experience
![](http://agri.nais.net.cn/resources/front/images/source_91.jpg)
Antimalarial activity, toxicity, pharmacokinetics and metabolic drug interaction of Plumbago Indica linn.
- 负责人:
- Kesara Na-Bangchang, Advisor
- 关键词:
- Plumbagin Antimalarial Plasmodium falciparum Plasmodium berghei Permeability Transport Efflux transporters Caco-2 cell P-glycoprotein Pharmacokinetics
- DOI:
- doi:10.14457/tu.the.2015.159
- 摘要:
- (270-490) nM, respectively. In vivo antimalarial activity was investigated in Plasmodium berghei infected mouse model. Chloroquine exhibited the mos
![](http://agri.nais.net.cn/resources/front/images/source_91.jpg)
Data from: The impact of within-host ecology on the fitness of a drug-resistant parasite
- 负责人:
- 关键词:
- rodent malaria;fitness cost;within-host competition;Drug resistance;malaria;Plasmodium chabaudi
- DOI:
- doi:10.5061/dryad.1g2n6d2
- 摘要:
- when resistance was rarer to begin with. Methodology: We infected mice with varying densities of drug-resistant Plasmodium chabaudi malaria parasites in a fixed
![](http://agri.nais.net.cn/resources/front/images/source_91.jpg)
Data from: Opportunities and challenges of Integral Projection Models for modeling host-parasite dynamics
- 负责人:
- 关键词:
- Integral Projection Model parasite demography infectious disease dynamics murine malaria measles
- DOI:
- doi:10.5061/dryad.07mc1
- 摘要:
- categorization and/or agent-based approaches. Integral Projection Models (IPMs) allow variance in individual trajectories of quantitative traits and thei
![](http://agri.nais.net.cn/resources/front/images/source_91.jpg)
Data from: Adaptive periodicity in the infectivity of malaria gametocytes to mosquitoes
- 负责人:
- DOI:
- doi:10.5061/dryad.g0j11kf
- 摘要:
- , this may select for rhythms in immune defence. We examine rhythms in the density and infectivity of transmission forms (gametocytes) of rodent malaria par
![](http://agri.nais.net.cn/resources/front/images/source_91.jpg)
Data from: Aggressive chemotherapy and the selection of drug resistant pathogens
- 负责人:
- DOI:
- doi:10.5061/dryad.09qc0
- 摘要:
- in vivo in conjunction with measures of clinical outcomes and infectiousness. Using rodent malaria in laboratory mice, we found that less aggressive