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Data from: Quantitative time-resolved analysis reveals intricate, differential regulation of standard- and immuno-proteasomes
负责人:
关键词:
proteasome;short fluorogenic peptides
DOI:
doi:10.5061/dryad.nk453
摘要:
of immunological processes. Despite its importance the mechanisms regulating proteasome activity are only incompletely understood. Here we use an ite
Data from: A large fraction of HLA class I ligands are proteasome-generated spliced peptides
负责人:
关键词:
proteasome;antigen presentation;proteasome-catalyzed peptide splicing;immunopeptidome;HLA class I-restricted epitopes;EThcD
DOI:
doi:10.5061/dryad.r984n
摘要:
The proteasome generates the epitopes presented on human leukocyte antigen (HLA) class I molecules that elicit CD8+ T cell responses. Reports
Data from: Selective clearance of the inner nuclear membrane protein emerin by vesicular transport during ER stress
负责人:
关键词:
protein turnover;Mus musculus;proteomics;protein homeostasis
DOI:
doi:10.5061/dryad.n0r525h
摘要:
ng a microscopy approach, we observed that the proteasome can degrade INM proteins in situ. However, we also uncovered evidence for selective, vesicular transport
Data from: Host interaction analysis of PA-N155 and PA-N182 in chicken cells reveals an essential role of UBA52 for replication
负责人:
关键词:
DOI:
doi:10.5061/dryad.77r8m5g
摘要:
d to signaling pathways of proteasome, ribosome, and aminoacy1-tRNA biosynthesis were significantly enriched, suggesting their potential roles in H5N1 IAV infection
Data from: The loss of hemoglobin and myoglobin does not minimize oxidative stress in Antarctic icefishes
负责人:
关键词:
Notothenia coriiceps;Pseudochaenichthys georgianus;Champsocephalus gunnari;Chaenocephalus aceratus;Antarctic fish;hemoglobin;myoglobin;Oxidative stress;Gobionotothen gibberifrons;Chionodraco rastrospinosus
DOI:
doi:10.5061/dryad.5228g
摘要:
of ubiquitinated proteins and rates of protein degradation by the 20S proteasome were also quantified. Although levels of oxidized proteins and lipids, ubiquitinated prote
Data from: Regulation of HBEGF by micro-RNA for survival of developing human trophoblast cells
负责人:
关键词:
protein turnover;Next-generation sequencing;oxygen concentration;MiRNA;DGCR8;3\u2019UTR;translational regulation;trophoblast;HBEGF
DOI:
doi:10.5061/dryad.gf1bq
摘要:
at 20% O2 than 2% O2, mediated by the proteasome. However, proteasome inhibition failed to initiate HBEGF accumulation at 20% O2. Reporte
Data from: Positive cytoplasmic UCHL5 tumor expression in gastric cancer is linked to improved prognosis
负责人:
关键词:
proteasome;prognostic marker;gastric cancer;UCHL5
DOI:
doi:10.5061/dryad.89qr5
摘要:
w biomarkers for clinical use are essential. Recently, we reported that the proteasome-associated deubiquitinating enzyme UCHL5/Uch37 is a new pro
Data from: Screen for mitochondrial DNA copy-number maintenance genes reveals essential role for ATP synthase
负责人:
关键词:
DOI:
doi:10.5061/dryad.v55p5
摘要:
rized components of the mtDNA replication and transcription machineries, positives included many proteins of the cytosolic proteasome and ribosom
Data from: Cyclin dependent kinase 5 (CDK5) regulates the circadian clock
负责人:
关键词:
proteasome;Period2;nuclear localisation;Cryptochrome1;Mus musculus;phosphorylation
DOI:
doi:10.5061/dryad.4067r78
摘要:
is the translocation of clock components into the nucleus, which is regulated in many cases by kinases. In mammals, the kinase promoting the nuclear import of the key
Data from: Oxidative stress-mediated NF?B phosphorylation upregulates p62/SQSTM1 and promotes retinal pigmented epithelial cell survival throug
负责人:
关键词:
autophagy;RPE;ATG10;p62\/SQSTM1;Age-related macular degeneration;NF?B p65;Oxidative stress
DOI:
doi:10.5061/dryad.2gn8c
摘要:
egulation in response to oxidative stress. Proteasome inhibition by H2O2 causes p62-NF?B signaling as antioxidant pre-treatment reversed p62 expr

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