Data from: Pre-adapting parasitic phages to a pathogen leads to increased pathogen clearance and lowered resistance evolution

负责人：

关键词：

pathogenesis;antagonism;Experimental evolution;phage therapy;Host-parasite interaction

DOI：

doi:10.5061/dryad.t285m

摘要：

rise in antibiotic resistance. However, a major limitation of phage therapy is the ease at with bacteria can evolve resistance to phages. Her

Data from: Targeting antibiotic resistant bacteria with phages reduces bacterial density in an insect host

负责人：

Mikonranta, Lauri

关键词：

bacteriophage antibiotic resistance gut infection insect model phage therapy

DOI：

doi:10.5061/dryad.sc54383

摘要：

Phage therapy is attracting growing interest among clinicians as antibiotic resistance continues becoming harder to control. However, clinical trials

Data from: Exposure to phages has little impact on the evolution of bacterial antibiotic resistance on drug concentration gradients

负责人：

关键词：

Biomedicine;Species Interactions;Experimental evolution;Adaptation

DOI：

doi:10.5061/dryad.f9h64

摘要：

The use of phages for treating bacterial pathogens has recently been advocated as an alternative to antibiotic therapy. Here we test a hypothesis tha

Data from: Back to the future: evolving bacteriophages to increase their effectiveness against the pathogen Pseudomonas aeruginosa PAO1

负责人：

关键词：

Adaptation Biomedicine Evolutionary Medicine Experimental Evolution virulence cross infection disinfection phage therapy

DOI：

doi:10.5061/dryad.5hf57

摘要：

to combat pathogenic bacteria through their application in phage therapy. Here we capitalize on previous studies showing how evolution may increase phage

Data from: Parasites and competitors suppress bacterial pathogen synergistically due to evolutionary trade-offs

负责人：

关键词：

fitness cost;Ralstonia solanacearum;phage therapy;trade-off;Experimental evolution;interference competition

DOI：

doi:10.5061/dryad.m009s

摘要：

t while the phage had a small effect on pathogen densities on its own, it considerably increased the R. solanacearum sensitivity to antibiotics produced

Data from: Phage combination therapies for bacterial wilt disease in tomato

负责人：

关键词：

microbial ecology;microbiome;population dynamics;agroecology;environmental biotechnology;Bacteriophage;Ralstonia solanacearum;tomato

DOI：

doi:10.5061/dryad.02v6wwpzq

摘要：

with enrichment for bacterial species that were antagonistic towards Ralstonia solanacearum. Phage treatment did not affect existing rhizosphere microbiota

Data from: Evolutionary dynamics of separate and combined exposure of Pseudomonas fluorescens SBW25 to antibiotics and bacteriophage

负责人：

关键词：

bacteria;antibiotic resistance;phage therapy;Experimental evolution;Pseudomonas;hypermutator

DOI：

doi:10.5061/dryad.4p49n3mj

摘要：

of the antibiotic rifampicin and the lytic bacteriophage SBW25?2. We then compared the densities, growth rates, and the mutations at the rpoB locus leading