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Data from: Single?cell profiling screen identifies microtubule?dependent reduction of variability in signaling
- 负责人:
- DOI:
- doi:10.5061/dryad.67bc0
- 摘要:
- d genetic and chemical perturbations to show that, without microtubules, PRS output is reduced but variability is unaffected, while, when microtubules are pr
Data from: A mathematical understanding of how cytoplasmic dynein walks on microtubules
- 负责人:
- DOI:
- doi:10.5061/dryad.1615h
- 摘要:
- associated with diverse cellular activities (AAA+ rings) and the microtubule binding domains which allow dynein to bind to microtubules. This mathematical framework
Data from: Measuring NDC80 binding reveals the molecular basis of tension-dependent kinetochore-microtubule attachments
- 负责人:
- 关键词:
- Homo Sapiens
- DOI:
- doi:10.5061/dryad.14rr125
- 摘要:
- on fluorescence lifetime imaging microscopy and F?rster resonance energy transfer, to quantitatively measure the fraction of NDC80 complexes bound to microtubules at individual kinetochores
Data from: Automated stitching of microtubule centerlines across serial electron tomograms
- 负责人:
- DOI:
- doi:10.5061/dryad.v8j20
- 摘要:
- Tracing microtubule centerlines in serial section electron tomography requires microtubules to be stitched across sections, that is lines from diffe
Data from: Nanoscopic imaging of thick heterogeneous soft-matter structures in aqueous solution
- 负责人:
- DOI:
- doi:10.5061/dryad.c2j90
- 摘要:
- us matter with submicroscopic spatial resolution in aqueous solution. By imaging both individual microtubules and collagen fibrils in a network
Data from: A quantitative proteomic analysis of cofilin phosphorylation in myeloid cells and its modulation using the LIM kinase inhibitor Pyr1
- 负责人:
- DOI:
- doi:10.5061/dryad.4n5929c
- 摘要:
- LIM kinases are located at a strategic crossroad, downstream of several signaling pathways and upstream of effectors such as microtubules
Data from: High-resolution chemical dissection of a model eukaryote reveals targets, pathways and gene functions
- 负责人:
- DOI:
- doi:10.5061/dryad.v5m8v
- 摘要:
- for (i) novel compounds with a similar mechanism of action acting upon microtubules or vacuolar ATPases, and (ii) an un-annotated ORF, YIL060w, that plays a ro
Data from: A virus responds instantly to the presence of the vector on the host and forms transmission morphs
- 负责人:
- Drucker, Martin
- DOI:
- doi:10.5061/dryad.pd658
- 摘要:
- o microtubules throughout the cell. Enhancing or inhibiting this TB reaction pharmacologically or by using a mutant virus enhanced or inhibited transmission, res
Data from: Impact of genetic reduction of NMNAT2 on chemotherapy-induced losses in cell viability in vitro and peripheral neuropathy in vivo
- 负责人:
- DOI:
- doi:10.5061/dryad.1rr87
- 摘要:
- (NMNAT1 or NMNAT3), NMNAT enzyme activity (i.e. NAD/NADH levels) or microtubule associated protein-2 (MAP2) or neurofilament protein levels. We ther
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