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In vivo Study of the Effects of a Northern Contaminant Mixture (NCM) on the Development of Metabolic and Cardiovascular Diseases under Condi
- 负责人：
- Canadian Polar Data Network (CPDN)
- 关键词：
- Disease Diet Heavy metal Lifestyle Methylmercury Persistent organic pollutants (POPs) Northern Contaminants Program
- DOI：
- doi:10.5443/12422
- 摘要：
- tigate the potential role of exposure to Northern contaminants in the development of metabolic and cardiovascular diseases using rodent models of human disease, the obese
Data from: Metatranscriptomics of the human oral microbiome during health and disease
- 负责人：
- DOI：
- doi:10.5061/dryad.d41v4
- 摘要：
- -associated microbial communities undergo conserved changes in metabolism during disease. Here we used patient-matched healthy and diseased samples
Data from: Discovery of metabolic biomarkers for Duchenne Muscular Dystrophy within a natural history study
- 负责人：
- DOI：
- doi:10.5061/dryad.qg6q2
- 摘要：
- in healthy controls. Overall, this study yielded promising metabolic signatures that could prove useful to monitor DMD disease progression and response
Data from: Tumor suppressor RARRES1- a novel regulator of fatty acid metabolism in epithelial cells
- 负责人：
- DOI：
- doi:10.5061/dryad.6t1m4k4
- 摘要：
- for metabolic reprogramming and identify RARRES1 as a potential target for cancers and other diseases with impaired fatty acid metabolism.
Data from: Saposin B deficiency as a cause of adult-onset metachromatic leukodystrophy
- 负责人：
- DOI：
- doi:10.5061/dryad.ps15hf5
- 摘要：
- N/A
Data from: Identifying metabolic subpopulations from population level mass spectrometry
- 负责人：
- 关键词：
- DOI：
- doi:10.5061/dryad.gf80t
- 摘要：
- ng can lead to disease and aging. In addition, metabolic heterogeneity can have biological consequences, such as differences in outcomes and drug
Data from: Myeloperoxidase oxidation of methionine associates with early cystic fibrosis lung disease
- 负责人：
- DOI：
- doi:10.5061/dryad.55m2m81
- 摘要：
- . Further studies are needed to establish whether methionine oxidation directly contributes to early CF lung disease and explore potential
Data from: Metabolite profile of a mouse model of Charcot-Marie-Tooth type 2D neuropathy: implications for disease mechanisms and interventions
- 负责人：
- Burgess, Robert W.
- DOI：
- doi:10.5061/dryad.ng07t
- 摘要：
- . To identify putative disease mechanisms, we compared metabolites isolated from the spinal cord of Gars mutant mice and their littermate controls. A profile
Data from: Discovery of potential urine-accessible metabolite biomarkers associated with muscle disease and corticosteroid response in the mdx mouse
- 负责人：
- 关键词：
- DOI：
- doi:10.5061/dryad.v42h23k
- 摘要：
- ng associated with disease status. These included a metabolite with m/z = 357 and creatine, which were also reported in a previous human study looking at serum. Nove
Data from: Long-lived metabolic enzymes in the crystalline lens identified by pulse-labeling of mice and mass spectrometry
- 负责人：
- DOI：
- doi:10.5061/dryad.r6h8dr2
- 摘要：
- activities has been implicated in age-related cataracts, and other lens diseases. However, the lenticular protein dynamics underlying health and disease
