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Data from: Myeloperoxidase oxidation of methionine associates with early cystic fibrosis lung disease
- 负责人：
- DOI：
- doi:10.5061/dryad.55m2m81
- 摘要：
- Rationale: Cystic fibrosis (CF) lung disease progressively worsens from infancy to adulthood. Disease-driven changes in early CF airway fluid
Data from: Stratified assessment of the role of inhaled hypertonic saline in reducing cystic fibrosis pulmonary exacerbations
- 负责人：
- DOI：
- doi:10.5061/dryad.491d1
- 摘要：
- Objective: Limited data exist concerning the role of inhaled hypertonic saline (HS) in decreasing pulmonary exacerbations in cystic fibrosis (CF
Data from: High virulence sub-populations in Pseudomonas aeruginosa long-term cystic fibrosis airway infections
- 负责人：
- DOI：
- doi:10.5061/dryad.p7d03
- 摘要：
- Background: Pseudomonas aeruginosa typically displays loss of virulence-associated secretions over the course of chronic cystic fibrosis infections
RAS-modification as a novel therapy for pulmonary indications in T2D
- 负责人：
- 关键词：
- Clinical and Experimental Therapeutics T2DM angiotensin(1-7) immune function lung fibrosis pulmonary indications
- DOI：
- doi:10.25549/usctheses-c40-350071
- 摘要：
- , inflammation, hypertrophy and fibrosis. New therapeutic targets are needed that consider both immune and structural components of lung health. RAS-modifying
Data from: An integrative computational approach for a prioritization of key transcription regulators associated with nanomaterial-induced toxicity
- 负责人：
- 关键词：
- DOI：
- doi:10.5061/dryad.3b025hh
- 摘要：
- this approach, we used published transcriptomic data derived from mice lung tissue exposed to carbon nanotubes (NM-401 and NRCWE-26). Because fibrosis is the mos
Data from: Relevance of heterokaryosis for adaptation and azole-resistance development in Aspergillus fumigatus
- 负责人：
- DOI：
- doi:10.5061/dryad.fr3kt2d
- 摘要：
- by recombination and mutation supply respectively. However, in certain Aspergillus diseases, such as cystic fibrosis and chronic pulmonary aspergillosis
Data from: Rapid diversification of Pseudomonas aeruginosa in cystic fibrosis lung-like conditions
- 负责人：
- 关键词：
- SCFM;Experimental evolution;Pathogen evolution;Adaptation;Pseudomonas aeruginosa;diversification
- DOI：
- doi:10.5061/dryad.5c38fv8
- 摘要：
- Chronic infection of the cystic fibrosis (CF) airway by the opportunistic pathogen Pseudomonas aeruginosa is the leading cause of morbidity
Therapeutic potential of rhesus theta (θ) defensin-1 in cystic fibrosis airway infection and inflammation
- 负责人：
- 关键词：
- Clinical and Experimental Therapeutics cystic fibrosis infection inflammation preclinical drug development
- DOI：
- doi:10.25549/usctheses-c40-309144
- 摘要：
- Cystic fibrosis (CF) is the most common life-limiting genetic disorder in Caucasians. The majority of the morbidity and mortality is attrib
tance evolution with Pseudomonas aeruginosa cystic fibrosis bacterial isolates
- 负责人：
- DOI：
- doi:10.5061/dryad.t285m
- 摘要：
- nic cystic fibrosis Pseudomonas aeruginosa lung isolates to four different phages. We first pre-adapted all phage strains against all bacterial strains
Data from: Requirements and access needs of patients with chronic disease to their hospital electronic health record: results of a cross-sectional
- 负责人：
- DOI：
- doi:10.5061/dryad.1pm91
- 摘要：
- , including a patient ranking of functionality. Setting: Secondary care patients attending a regional cystic fibrosis unit in the north of England Participants
