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Data from: Heterochromatin Protein 1? (HP1?) has distinct functions and distinct nuclear distribution in pluripotent versus differentiated cells
- 负责人：
- DOI：
- doi:10.5061/dryad.0c116
- 摘要：
- Background: Pluripotent embryonic stem cells (ESCs) have the unique ability to differentiate into every cell type and to self-renew. These
Data from: The transcription factor Pou3f1 promotes neural fate commitment via activation of neural lineage genes and inhibition of exte
- 负责人：
- DOI：
- doi:10.5061/dryad.3vk1g
- 摘要：
- of pluripotent stem cells through a dual role, activating internal neural induction programs and antagonizing extrinsic neural inhibitory signals.
Data from: Expression profiling of human pluripotent stem cell-derived cardiomyocytes exposed to doxorubicin—integration and visualization of multi
- 负责人：
- DOI：
- doi:10.5061/dryad.g335f
- 摘要：
- y be involved. In this study, we investigated doxorubicin-induced cardiotoxicity in human pluripotent stem cell-derived cardiomyocytes using prote
Data from: Simultaneous measurement of excitation-contraction coupling parameters identifies mechanisms underlying contractile responses of hiP
- 负责人：
- DOI：
- doi:10.5061/dryad.67c92vm
- 摘要：
- Cardiomyocytes from human induced pluripotent stem cells (hiPSC-CMs) are increasingly recognized as valuable for determining the effects of drugs
Data from: Collagen vitrigel promotes hepatocytic differentiation of induced pluripotent stem cells into functional hepatocyte-like cells
- 负责人：
- 关键词：
- Homo Sapiens;hepatocytic differentiation;in vitro differentiation;induced pluripotent stem cells
- DOI：
- doi:10.5061/dryad.5f3s52r
- 摘要：
- Differentiation of stem cells to hepatocytes provides an unlimited supply of human hepatocytes and therefore has been vigorously studied. Howeve
Development of targeted therapies for peroxisome biogenesis disorders
- 负责人：
- 关键词：
- Molecular Biology peroxisome biogenesis disorders peroxins PEX1 high-content screening small molecules induced pluripotent stem cells HepG2 cells Pex1-p.G844D mouse
- DOI：
- doi:10.25549/usctheses-c40-298640
- 摘要：
- the development of new model systems of PBDs, including induced pluripotent stem cells (iPSCs), HepG2 cells and mice. We generated iPSCs from primary skin fibroblasts
Data from: Cardiomyocyte mechanodynamics under conditions of actin remodelling
- 负责人：
- DOI：
- doi:10.5061/dryad.pf012v0
- 摘要：
- mechanical analysis of thousands of cells with a throughput exceeding 1,000 cells per second. For cardiomyocytes derived from human induced pluripotent stem cells
Data from: Arsenic induces members of the mmu-miR-466-669 cluster which reduces NeuroD1 expression
- 负责人：
- DOI：
- doi:10.5061/dryad.sc281
- 摘要：
- red miRNA expression was a mechanism by which arsenic inhibited cellular differentiation. The pluripotent P19 mouse embryonal carcinoma cells were expo
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