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Data from: Variations in HLA-B cell surface expression, half-life and extracellular antigen receptivity
- 负责人:
- 关键词:
- DOI:
- doi:10.5061/dryad.f0s23r8
- 摘要:
- The highly polymorphic human leukocyte antigen (HLA) class I molecules present peptide antigens to CD8+ T cells, inducing immunity against infecti
Data from: Men’s preferences for women’s body odours are not associated with HLA
- 负责人:
- Knoch, Daria
- 关键词:
- major histocompatibility complex MHC human leukocyte antigen mating preference heterozygosity olfaction
- DOI:
- doi:10.5061/dryad.270h8
- 摘要:
- human leucocyte antigen, HLA, in humans). While there is strong experimental support for MHC-associated mating behaviour in animals, the situation in humans is more complex
Data from: Generation of a monoclonal antibody recognizing the heavily glycosylated CD45 Protein and its application on identi
- 负责人:
- DOI:
- doi:10.5061/dryad.gg0nk
- 摘要:
- in in eukaryotic cells and using it as an antigen to generate CD45-targeting mAbs in mice. The mAbs generated showed robust affinity and specificity, which are crucial
Data from: TAPBPR mediates peptide dissociation from MHC class I using a leucine lever
- 负责人:
- DOI:
- doi:10.5061/dryad.p5k0156
- 摘要:
- cur by different mechanisms dependent on the C-terminal residue that the MHC I accommodates in its F pocket and provide novel insights that may inform the therapeutic potenti
Data from: Phased whole-genome genetic risk in a family quartet using a major allele reference sequence
- 负责人:
- 关键词:
- DOI:
- doi:10.5061/dryad.34q0d
- 摘要:
- methodology for Human Leukocyte Antigen typing that contributes to disease risk prediction. Finally, we advance methods for analysis of disease
Data from: A large fraction of HLA class I ligands are proteasome-generated spliced peptides
- 负责人:
- DOI:
- doi:10.5061/dryad.r984n
- 摘要:
- The proteasome generates the epitopes presented on human leukocyte antigen (HLA) class I molecules that elicit CD8+ T cell responses. Reports
Data from: Peripheral blood mitochondrial DNA copy number is associated with prostate cancer risk and tumor burden
- 负责人:
- DOI:
- doi:10.5061/dryad.88896
- 摘要:
- Gleason score and advanced tumor stage, but not serum prostate-specific antigen level (P = 0.002, 0.012 and 0.544, respectively). These findings of the present
Data from: Empty conformers of HLA-B preferentially bind CD8 and regulate CD8+ T cell function
- 负责人:
- 关键词:
- DOI:
- doi:10.5061/dryad.543pp71
- 摘要:
- When complexed with antigenic peptides, human leukocyte antigen (HLA) class I (HLA-I) molecules initiate CD8+ T cell responses via interacti
Data from: MHC-dependent mate preferences in humans
- 负责人:
- Wedekind, Claus
- DOI:
- doi:10.5061/dryad.r87pq
- 摘要:
- One substantial benefit of sexual reproduction could be that it allows animals (including humans) to react rapidly to a conti
Data from: Flexibility of fetal tolerance: Immune function during pregnancy varies between ecologically distinct populations
- 负责人:
- DOI:
- doi:10.25349/D94C77
- 摘要:
- populations experiencing evolutionarily novel conditions (e.g. reduced pathogen exposure), which may shape maternal response to fetal antigens. This study
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