Exploration of the role of ARHGEF10 in human disease

负责人：

关键词：

Biochemistry and Molecular Medicine ARHGEF10 Charcot-Marie-Tooth Disease CMT cancer neuropathy peripheral neuropathy protein rare disease genetics

DOI：

doi:10.25549/usctheses-c40-496015

摘要：

Rho guanine nucleotide exchange factors (RhoGEFs) are known for their role as catalysts of Rho family small guanosine triphosphatase (Rho GTPase

Data from: A RhoG-mediated signaling pathway that modulates invadopodia dynamics in breast cancer cells

负责人：

关键词：

guanine nucleotide-exchange factor;guanine-nucleotide exchange factors;invadopodia;Rho GTPases;SGEF;cytoskeleton;RhoG;Cell Migration;paxillin;Breast Cancer;cell invasion;rac1

DOI：

doi:10.5061/dryad.q1j50

摘要：

dynamics. We also show that SGEF is the exchange factor responsible for the activation of RhoG during invadopodia disassembly. When the expression of either

Data from: Selective sets of mRNAs localize to extracellular paramural bodies in the rice glup6 mutant line

负责人：

Okita, Thomas W.

关键词：

DOI：

doi:10.5061/dryad.sn878g4

摘要：

The transport of rice glutelin storage proteins to the storage vacuoles requires Rab5 and its cognate guanine nucleotide exchange factor (Rab5-GE