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Data from: Increased sensitivity of DNA damage response-deficient cells to stimulated microgravity-induced DNA lesions
- 负责人:
- DOI:
- doi:10.5061/dryad.3vc83
- 摘要:
- tability in cells with DNA damage response (DDR) defects.
Data from: Genome-wide CRISPR synthetic lethality screen identifies a role for the ADP-ribosyltransferase PARP14 in replication fork
- 负责人:
- 关键词:
- dna damage response
- DOI:
- doi:10.5061/dryad.p8cz8w9mj
- 摘要:
- The DNA damage response is essential to maintain genomic stability, suppress replication stress, and protect against carcinogenesis. The ATR-CHK1
Data from: Dissecting molecular stress networks: identifying nodes of divergence between life-history phenotypes
- 负责人:
- DOI:
- doi:10.5061/dryad.sb30r
- 摘要:
- d in their life-history phenotypes, vary concomitantly at candidate nodes of the stress response network, (i) under unstressed conditions and (ii) in response
Data from: Transcriptional remodeling upon light removal in a model cnidarian: losses and gains in gene expression
- 负责人:
- Leach, Whitney B.
- DOI:
- doi:10.5061/dryad.pp5qk07
- 摘要:
- shifted. Most surprisingly, thousands of genes, some of which are involved in oxidative stress, DNA damage response, and chromatin modification, ha
Data from: Comparative genotoxicity of TEMPO and three of its derivatives in mouse lymphoma cells
- 负责人:
- 关键词:
- DOI:
- doi:10.5061/dryad.v1955
- 摘要:
- damaging dose-responses of the test articles were compared using the PROAST benchmark dose (BMD) software package. The potency ranking of the four nitroxides
Data from: Chronic exposure to low-dose radiation at Chernobyl favours adaptation to oxidative stress in birds
- 负责人:
- DOI:
- doi:10.5061/dryad.rb5hr
- 摘要:
- hormetic effects following an adaptive response. Analysis of the phylogenetic signal supports the existence of adaptation in the studied traits, particular
Data from: Maintenance of age in human neurons generated by microRNA-based neuronal conversion of fibroblasts
- 负责人:
- DOI:
- doi:10.5061/dryad.t6096
- 摘要:
- ) to DNA methylation data revealed that the epigenetic ages of fibroblasts were highly correlated with corresponding age estimates of reprogrammed neurons. Trans
Data from: Molecular and iridescent feather reflectance data reveal recent genetic diversification and phenotypic differentiation in a cloud fores
- 负责人:
- DOI:
- doi:10.5061/dryad.88589
- 摘要:
- The present day distribution and spatial genetic diversity of Mesoamerican biota reflects a long history of responses to habitat change
Data from: Comparisons of behavioral and TRPA1 heat sensitivities in three sympatric Cuban Anolis lizards
- 负责人:
- DOI:
- doi:10.5061/dryad.v937tb5
- 摘要:
- owed distinct gene expression patterns in response to temperature stimuli, suggesting the genetically distinct thermal physiology among species. To inves
Data from: Epigenetic alterations and decreasing insecticide sensitivity of the Asian tiger mosquito Aedes albopictus
- 负责人:
- DOI:
- doi:10.5061/dryad.6t5n0
- 摘要:
- . Thus, epigenetics displays an important environmentally responsive element. The transgenerational impact of environmental stressors on DNA