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Pancreatic cancer: a review on biology, genetics and therapeutics
负责人:
关键词:
therapeutics Pharmaceutical Sciences pancreatic cancer cancer biology genetics
DOI:
doi:10.25549/usctheses-c3-516607
摘要:
of this complex disease. Such strategies seem to hold a great promise in diagnosis prevention and treatment of this disease.
Data from: Axial symptoms predict mortality in patients with Parkinson disease with subthalamic stimulation
负责人:
关键词:
Parkinson's disease;subthalamic nucleus;mortality;disease progression;deep brain stimulation;Paris
DOI:
doi:10.5061/dryad.6n70v4b
摘要:
, including interactions between treatment conditions and time to determine how treatments changed efficacy. We used joint models to link progression
Data from: Prophylactic digoxin treatment reduces IL-17 production in vivo in the neonatal calf and moderates RSV-associated disease
负责人:
关键词:
DOI:
doi:10.5061/dryad.72db024
摘要:
in rodent models of autoimmune disease. We demonstrate here that in vitro and in vivo digoxin treatment also inhibits IL-17 production by bovine leukocytes
Data from: Revisiting protein aggregation as pathogenic in sporadic Parkinson’s and Alzheimer’s diseases
负责人:
Espay, Alberto J.
关键词:
Parkinson’s disease Alzheimer’s disease biomarkers disease modifying treatments clinical trials
DOI:
doi:10.5061/dryad.g1nq02r
摘要:
aggregates may be relevant to common pathology but not to subgroup pathogenesis, and (2) disease-modifying treatments targeting oligomers or fibrils mig
Data from: Population-scale treatment informs solutions for control of environmentally transmitted wildlife disease
负责人:
关键词:
Wildlife disease management;Sarcoptes scabiei<\/i>;Sarcoptes scabiei;Sarcoptic mange;environmental transmission;bare-nosed wombat;Host-disease modelling;Vombatus ursinus<\/i>;Vombatus ursinus
DOI:
doi:10.5061/dryad.0fs2vn4
摘要:
fficult for environmentally transmitted pathogens, including some of the most conservation-critical wildlife diseases. 2. We undertook a treatment program aimed at population
RAS-modification as a novel therapy for pulmonary indications in T2D
负责人:
关键词:
Clinical and Experimental Therapeutics T2DM angiotensin(1-7) immune function lung fibrosis pulmonary indications
DOI:
doi:10.25549/usctheses-c40-350071
摘要:
administration of A(1-7) to db/db mice is effective in prevention of progression of lung disease in db/db mice. Treatment prevented pathological remodelin
Data from: Development of an adrenocortical cancer humanized mouse model to characterize anti-PD1 effects on tumor microenvironment
负责人:
关键词:
Adrenocortical carcinoma;immunotherapy;humanized mouse PDX model;anti-PD-1
DOI:
doi:10.5061/dryad.f8q4350
摘要:
with metastatic disease. Results: Characterization of the CU-ACC2-hu-CB-BRGS model confirmed ACC origin and match with the original human tumor. Treatment of the mice
Data from: Modelling the potential efficacy of treatments for white-nose syndrome in bats
负责人:
关键词:
disease treatment modelling;emerging infectious diseases;fungal pathogen;Wildlife disease management;conservation;Pseudogymnoascus destructans;white-nose syndrome
DOI:
doi:10.5061/dryad.08kprr4zv
摘要:
" lang="en-US">nt color="#000000">nt>2. We use population viability models to test if a hypothetical WNS treatment or management action could
Data from: Critical disease windows shaped by stress exposure alter allocation trade-offs between development and immunity
负责人:
关键词:
glucocorticoid;ranavirus;Lithobates sylvaticus Rana sylvatica;larvae;amphibian;corticosterone;metamorphosis
DOI:
doi:10.5061/dryad.7q33j
摘要:
and disease processes because the neuroendocrine stress axis coordinates developmental remodeling, immune function, and energy allocation in larval amphibians
Data from: Screening of health care workers for tuberculosis: development and validation of a new health economic model to inform practice
负责人:
关键词:
Tuberculosis;Health economics;Immunology
DOI:
doi:10.5061/dryad.7576g50f
摘要:
BACKGROUND: Methods for determining cost-effectiveness of different treatments are well established, unlike appraisal of non-drug intervent

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