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Data from: Artificial selection sheds light on developmental mechanisms of limb elongation
- 负责人：
- DOI：
- doi:10.5061/dryad.0g1f2
- 摘要：
- , but the heritable cellular processes that drove this evolution within species are poorly understood. In this study, we take a novel “micro-evo-devo” approach, usi
Data from: The origins of novelty from within the confines of homology: the developmental evolution of the digging tibia of dung beetles
- 负责人：
- DOI：
- doi:10.5061/dryad.460hn37
- 摘要：
- of novelty in evolution assumes the absence of homology, yet where homology ends and novelty begins is increasingly difficult to parse as evo devo continuously
Data from: A homeotic shift late in development drives mimetic color variation in a bumble bee
- 负责人：
- DOI：
- doi:10.5061/dryad.3v6f25v
- 摘要：
- Natural phenotypic radiations, with their high diversity and convergence, are well-suited for informing how genomic changes translate to natural phenotypic variation. New genomic tools enable discovery in such traditionally non-model systems. Here, we characterize the genomic basis of color pattern variation in bumble bees (Hymenoptera, Apidae, Bombus), a group that has undergone extensive convergence of setal color patterns as a result of Müllerian mimicry. In western North America, multiple species converge on local mimicry patterns through parallel shifts of mid-abdominal segments from red to black. Using genome-wide association we establish that a cis-regulatory locus between the abdominal fate-determining Hox genes, abd-A and Abd-B, controls the red-black color switch in a western species, Bombus melanopygus. Gene expression analysis reveals distinct shifts in Abd-B aligned with the duration of setal pigmentation at the pupal-adult transition. This results in atypical anterior Abd-B expression, a late developmental homeotic shift. Changing expression of Hox genes can have widespread effects given their important role across segmental phenotypes, however, the late timing reduces this pleiotropy, making Hox genes suitable targets. Analysis of this locus across mimics and relatives reveals that other species follow independent genetic routes to obtain the same phenotypes.
Onthophagus taurus Genome Assembly 1.0
- 负责人：
- 关键词：
- DOI：
- doi:10.15482/usda.adc/1255156
- 摘要：
- dung beetle and a focal taxon for studies in evolutionary ecology, evolutionary genetics, behavioral ecology, evo-devo and developmental genetics. Like ma
Data from: Baby fish working out: an epigenetic source of adaptive variation in the cichlid jaw
- 负责人：
- DOI：
- doi:10.5061/dryad.s8fn4
- 摘要：
- of evolutionary biology. While most evo-devo studies focus on the genetic underpinnings of adaptive phenotypic variation, factors beyond changes in nucleotide sequence
Data from: The unexpected depths of genome-skimming data: a case study examining Goodeniaceae floral symmetry genes
- 负责人：
- DOI：
- doi:10.5061/dryad.0500c
- 摘要：
- (e.g., plastomes); however, researchers may be overlooking data in low abundance that could be used for phylogenetic or evo-devo studies. Here, we present
Data from: Studying developmental variation with Geometric Morphometric Image Analysis (GMIA)
- 负责人：
- DOI：
- doi:10.5061/dryad.1fq87
- 摘要：
- The ways in which embryo development can vary across individuals of a population determine how genetic variation translates into adult phenotypic variation. The study of developmental variation has been hampered by the lack of quantitative methods for the joint analysis of embryo shape and the spatial distribution of cellular activity within the developing embryo geometry. By drawing from the strength of geometric morphometrics and pixel/voxel-based image analysis, we present a new approach for the biometric analysis of two-dimensional and three-dimensional embryonic images. Well-differentiated structures are described in terms of their shape, whereas structures with diffuse boundaries, such as emerging cell condensations or molecular gradients, are described as spatial patterns of intensities. We applied this approach to microscopic images of the tail fins of larval and juvenile rainbow trout. Inter-individual variation of shape and cell density was found highly spatially structured across the tail fin and temporally dynamic throughout the investigated period.
Data from: Genetic analyses in Lake Malawi cichlids identify new roles for Fgf signaling in scale shape variation
- 负责人：
- DOI：
- doi:10.5061/dryad.35cp405
- 摘要：
Elasmoid scales are the most common epithelial appendage among vertebrates, however an understanding of the genetic mechanisms that underlie variation in scale shape is lacking. Using an F2?mapping cross between morphologically distinct cichlid species, we identified >40 QTL for scale shape at different body positions. We show that while certain regions of the genome regulate variation in multiple scales, most are specific to scales at distinct positions. This suggests a degree of regional modularity in scale development. We also identified a single QTL for variation in scale shape disparity across the body. Finally, we screened a QTL hotspot for candidate loci, and identified the Fgf receptor?fgfr1b?as a prime target. Quantitative rtPCR and small molecule manipulation support a role for Fgf signaling in shaping cichlid scales. While Fgfs have previously been implicated in scale loss, these data reveal new roles for the pathway in scale shape variation.
Data from: Transcriptional changes during Daphnia pulex development indicate that the maturation decision resembles a rate more than a threshold
- 负责人：
- DOI：
- doi:10.5061/dryad.1rc0v
- 摘要：
- Maturation is a critical developmental process, and the age and size at which it occurs have important fitness consequences. Although maturation is remarkably variable, certain mechanisms, including a minimum size or state threshold, are proposed to underlie the process across a broad diversity of taxa. Recent evidence suggests that thresholds may themselves be developmentally plastic, and in the crustacean Daphnia pulex it is unclear whether maturation follows a threshold or is a gradual process more akin to a rate. Changes in gene expression across four instars before and during maturation were compared in a cDNA microarray experiment. Developmental stage was treated statistically both as a discontinuous and a continuous variable, to determine whether genes showed gradual or discrete changes in expression. The continuous analysis identified a greater number of genes with significant differential expression (45) than the discontinuous analysis (11). The majority of genes, including those coding for histones, factors relating to transcription and cell cycle processes, and a putative developmental hormone showed continuous increases or decreases in expression from the first to the fourth instar, suggestive of a prolonged and gradual maturation process. Three genes coding for a fused Vitellogenin/super-oxide dismutase showed increases in expression following the second instar and coincided with the posited maturation threshold, but even their expression increased in a continuous fashion.
Data from: Genetic basis of stage-specific melanism: a putative role for a cysteine sulfinic acid decarboxylase in insect pigmentation
- 负责人：
- Beldade, Patricia
- DOI：
- doi:10.5061/dryad.1925530c
- 摘要：
- Melanism, the overall darkening of the body, is a widespread form of animal adaptation to particular environments, and includes bookcase examples of evolution by natural selection, such as industrial melanism in the peppered moth. The major components of the melanin biosynthesis pathway have been characterized in model insects, but little is known about the genetic basis of life-stage specific melanism such as cases described in some lepidopteran species. Here, we investigate two melanic mutations of Bicyclus anynana butterflies, called Chocolate and melanine, that exclusively affect pigmentation of the larval and adult stages, respectively. Our analysis of Mendelian segregation patterns reveals that the larval and adult melanic phenotypes are due to alleles at different, independently segregating loci. Our linkage mapping analysis excludes the pigmentation candidate gene black as the melanine locus, and implicates the gene encoding a putative PLP-dependant cysteine sulfinic acid decarboxylase as the Chocolate locus. We show variation in coding sequence and in expression levels for this candidate larval melanism locus. This is the first study that suggests a biological function for this gene in insects. Our findings open up exciting opportunities to study the role of this locus in the evolution of adaptive variation in pigmentation, and the uncoupling of regulation of pigment biosynthesis across developmental stages with different ecologies and pressures on body coloration.
