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Data from: Myeloperoxidase oxidation of methionine associates with early cystic fibrosis lung disease
- 负责人：
- DOI：
- doi:10.5061/dryad.55m2m81
- 摘要：
- Rationale: Cystic fibrosis (CF) lung disease progressively worsens from infancy to adulthood. Disease-driven changes in early CF airway fluid
Data from: High virulence sub-populations in Pseudomonas aeruginosa long-term cystic fibrosis airway infections
- 负责人：
- DOI：
- doi:10.5061/dryad.p7d03
- 摘要：
- Background: Pseudomonas aeruginosa typically displays loss of virulence-associated secretions over the course of chronic cystic fibrosis infecti
Data from: Life in the cystic fibrosis upper respiratory tract influences competitive ability of the opportunistic pathogen Pseudomonas aeruginosa
- 负责人：
- DOI：
- doi:10.5061/dryad.0m801b4
- 摘要：
- to simultaneous selection on complex interacting traits. We examined how cystic fibrosis (CF) associated and environmental isolates of the opportunistic
Data from: Stratified assessment of the role of inhaled hypertonic saline in reducing cystic fibrosis pulmonary exacerbati
- 负责人：
- DOI：
- doi:10.5061/dryad.491d1
- 摘要：
- Objective: Limited data exist concerning the role of inhaled hypertonic saline (HS) in decreasing pulmonary exacerbations in cystic fibrosis (CF
Data from: Evaporimeter and bubble-imaging measures of sweat gland secretion rates
- 负责人：
- DOI：
- doi:10.5061/dryad.v3127
- 摘要：
- they provide a near-linear readout across almost the full range of CFTR function. They differentiate cystic fibrosis (CF) subjects from CF carriers and carriers
Data from: Making it last: storage time and temperature have differential impacts on metabolite profiles of airway samples from cystic fibrosis
- 负责人：
- DOI：
- doi:10.5061/dryad.qh100
- 摘要：
- Metabolites of human or microbial origin have the potential to be important biomarkers of disease state in cystic fibrosis (CF). Clinical sample collecti
Data from: The magnitude of ivacaftor effects on fluid secretion via R117H-CFTR channels: human in vivo measurements
- 负责人：
- DOI：
- doi:10.5061/dryad.8225n
- 摘要：
- agonists intradermally to stimulate CFTR-dependent ‘C-sweat’ and methacholine to stimulate ‘M-sweat’, which persists in CF subjects. We focused on an R117H-7T/F508del
Data from: Rapid diversification of Pseudomonas aeruginosa in cystic fibrosis lung-like conditions
- 负责人：
- 关键词：
- SCFM;Experimental evolution;Pathogen evolution;Adaptation;Pseudomonas aeruginosa;diversification
- DOI：
- doi:10.5061/dryad.5c38fv8
- 摘要：
- Chronic infection of the cystic fibrosis (CF) airway by the opportunistic pathogen Pseudomonas aeruginosa is the leading cause of morbidity
Data from: Requirements and access needs of patients with chronic disease to their hospital electronic health record: results of a cross-secti
- 负责人：
- DOI：
- doi:10.5061/dryad.1pm91
- 摘要：
- , including a patient ranking of functionality. Setting: Secondary care patients attending a regional cystic fibrosis unit in the north of England Partic
on with Pseudomonas aeruginosa cystic fibrosis bacterial isolates
- 负责人：
- DOI：
- doi:10.5061/dryad.t285m
- 摘要：
- cystic fibrosis Pseudomonas aeruginosa lung isolates to four different phages. We first pre-adapted all phage strains against all bacterial strains
