Data from: A quantitative proteomic analysis of cofilin phosphorylation in myeloid cells and its modulation using the LIM kinase inhibitor Pyr1

负责人：

关键词：

Lim kinases;leukemia;Mus musculus;cofilin;proteomics;Homo Sapiens;phosphorylation

DOI：

doi:10.5061/dryad.4n5929c

摘要：

and the actin cytoskeleton. Cofilin is the only LIM kinases substrate that is well described to date, and its phosphorylation on serine 3 by LIM kinases controls cofilin actin

LIM Domain Kinase 1 (LIMK1), Human Kinase Domain; A Target Enabling Package

负责人：

Eidarus Salah;;Beltrami, Alessandra;;Apirat Chaikuad;;Hanke, Thomas;;Kashima, Risa;;Canning, Peter;;Knapp, Susanne Muller;;Knaus, Petra;;Hata, Akiko;;Knapp, Stefan

关键词：

Structural Genomics Drug Discovery Chemical Biology

DOI：

doi:10.5287/bodleian:zg5naqjyk

摘要：

g via the kinase LIMK1. LIMK1 performs inhibitory phosphorylation on cofilin proteins blocking their actin-severing activity. Excessive BMPR2-LI

Data from: Phylogenetic patterns of codon evolution in the actin-depolymerizing factor/cofilin (adf/cfl) gene family

负责人：

关键词：

cofilin molecular evolution actin-depolymerizing factor

DOI：

doi:10.5061/dryad.4vb0j

摘要：

The actin-depolymerizing factor/cofilin (ADF/CFL) gene family encodes a diverse group of relatively small proteins. Once known strictly as modulators

Human Lim Domain Kinase 1 (Limk1), Kinase Domain; A Target Enabling Package

负责人：

关键词：

protein target enabling package disease structure cancer neuropsychiatry neuro neurological genetic disorders metabolic diseases oncology

DOI：

doi:10.5281/zenodo.1287260

摘要：

g via the kinase LIMK1. LIMK1 performs inhibitory phosphorylation on cofilin proteins blocking their actin-severing activity. Excessive BMPR2-LI

Human Lim Domain Kinase 1 (Limk1), Kinase Domain; A Target Enabling Package

负责人：

关键词：

protein target enabling package disease structure cancer neuropsychiatry neuro neurological genetic disorders metabolic diseases oncology

DOI：

doi:10.5281/zenodo.1241027

摘要：

g via the kinase LIMK1. LIMK1 performs inhibitory phosphorylation on cofilin proteins blocking their actin-severing activity. Excessive BMPR2-LI

Human LIM domain kinase 1 (LIMK1), kinase domain; A Target Enabling Package

负责人：

关键词：

protein target enabling package disease structure cancer neuropsychiatry neuro neurological genetic disorders metabolic diseases oncology

DOI：

doi:10.5281/zenodo.1219706

摘要：

g via the kinase LIMK1. LIMK1 performs inhibitory phosphorylation on cofilin proteins blocking their actin-severing activity. Excessive BMPR2-LI