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Data from: Evaluating in vitro-in vivo extrapolation of toxicokinetics
负责人:
关键词:
httk;in vitro-in vivo extrapolation;Rattus norvegicus;toxicokinetics;toxcast
DOI:
doi:10.5061/dryad.32v7b
摘要:
Prioritizing the risk posed by thousands of chemicals potentially present in the environment requires exposure, toxicity, and toxicokinetic (TK) data
Data from: Validation of the GARD?skin assay for assessment of chemical skin sensitizers – ring trial results of predictive performance and reproducibility
负责人:
Johansson, Henrik
关键词:
GARD GARDskin sensitization in vitro
DOI:
doi:10.5061/dryad.sc65030
摘要:
Proactive identification of chemicals with skin sensitizing properties is a key toxicological endpoint within chemical safety assessment. In order
Data from: High-throughput H295R steroidogenesis assay: utility as an alternative and a statistical approach to characterize effects
负责人:
关键词:
H295R;high-throughput screening;steroidogenesis;toxcast;Mahalanobis distance
DOI:
doi:10.5061/dryad.385j7
摘要:
, glucocorticoids, androgens, and estrogens. To date, 2012 chemicals have been screened at one concentration; of these, 656 chemicals have been screened
Data from: Ocean acidification during pre-fertilization chemical communication affects sperm success
负责人:
关键词:
DOI:
doi:10.5061/dryad.37pvmcvf2
摘要:
tion between sperm and egg-derived chemicals. These chemical signals, along with the physiological responses in sperm they elicit, are li
Use of Text-mining and Machine Learning Approaches to Conduct a Rapid Literature Survey on Environmental Chemicals and the Thyroid
负责人:
关键词:
Machine Learning Thyroid Text Mining
DOI:
doi:10.17632/6v2db93j29.1
摘要:
Literature Survey on Environmental Chemicals and the Thyroid" (Kiros et al., EI 2017) SWIFT-Review_Thyroid Literature Database.stp contains: 235,960 records
Data from: In silico site-directed mutagenesis informs species-specific predictions of chemical susceptibility derived from the Sequence Al
负责人:
关键词:
ecdysone receptor;docking simulations;acetylcholinesterase;sequence similarity
DOI:
doi:10.5061/dryad.2tg6967
摘要:
ross Species Susceptibility (SeqAPASS) tool was developed as a rapid, cost effective method to aid cross-species extrapolation of susceptibility to chemicals
Data from: Mathematical modelling of the vitamin C clock reaction
负责人:
关键词:
matched asymptotic expansions;clock reaction;mathematical chemistry
DOI:
doi:10.5061/dryad.68q4hf7
摘要:
applications. A substrate-depletive, non-autocatalytic clock reaction involving household chemicals (vitamin C, iodine, hydrogen peroxide and starch) is modelled
Data from: Chemical communication of queen supergene status in an ant
负责人:
关键词:
supergene;Formicidae;Gp-9;polygyny;Insecta;Arthropoda;Semiochemicals;Pheromones;Hymenoptera;Solenopsis invicta
DOI:
doi:10.5061/dryad.76r80
摘要:
behavioural assay to reveal that polygyne workers, many of which bear the Sb element, employ chemical cues on the cuticle of queens to achieve worker Sb
Data from: Teratological and behavioral screening of the National Toxicology Program 91-compound library in zebrafish (Danio rerio)
负责人:
关键词:
DOI:
doi:10.5061/dryad.r841282
摘要:
, polycyclic aromatic hydrocarbons (PAHs), drugs, industrial chemicals and pesticides. Fish were exposed to five concentrations of each chemical or an equal amount of vehicle (0.5% DMSO
Data from: Differential sensitivity to in vitro inhibition of cytochrome P450 aromatase (CYP19) activity among 18 freshwater fishes
负责人:
关键词:
DOI:
doi:10.5061/dryad.nn94830
摘要:
There is significant concern regarding potential impairment of fish reproduction associated with endocrine disrupting chemicals. Aromatase (CYP19

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