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Data from: Total A?42/A?40 ratio in plasma predict amyloid-PET status, independent of clinical AD diagnosis
- 负责人：
- DOI：
- doi:10.5061/dryad.f300d56
- 摘要：
- to neocortical amyloid beta (A?) burden via PET SUVR, and investigated both association with A?-PET status and correlation (and agreement) with SUVR. Result
Data from: Brain myo-inositol as a potential marker of amyloid-related pathology: a longitudinal study.
- 负责人：
- DOI：
- doi:10.5061/dryad.rd681sp
- 摘要：
- Objective: To investigate the association between longitudinal changes in proton magnetic spectroscopy (MRS) metabolites and amyloid pathology
Data from: The Golgi-localized ?-ear-containing ARF-binding (GGA) proteins alter amyloid-? precursor protein (APP) processing through interaction
- 负责人：
- 关键词：
- DOI：
- doi:10.5061/dryad.7qm89
- 摘要：
- Proteolytic processing of amyloid-? precursor protein (APP) by beta-site APP cleaving enzyme 1 (BACE1) is the initial step in the production
Data from: Amyloid and cerebrovascular burden divergently influence brain functional network changes over time
- 负责人：
- DOI：
- doi:10.5061/dryad.v5h2fd7
- 摘要：
- ; svMCI: 13 with two time-points, 16 with three time-points, 26 with four time-points). Results: Amyloid-? burden was associated with longitudinal DMN FC
Data from: CSF biomarkers of neuroinflammation and cerebrovascular dysfunction in early Alzheimer's disease
- 负责人：
- DOI：
- doi:10.5061/dryad.5f82b32
- 摘要：
- changes and study their associations with the core biomarkers of AD pathology (amyloid &[beta] (A&[beta]) and tau), structural imaging correlates
Noscapine Treatment Effect In Transgenic Mouse Model Of Alzheimer'S Disease
- 负责人：
- 关键词：
- Alzheimer's disease Transgenic mouse Magnetic resonance imaging Cerebral vascular reactivity Cerebral blood flow Cerebrovascular dysfunction
- DOI：
- doi:10.5281/zenodo.1209064
- 摘要：
- involving bradykinin receptor has been proposed at the nexus of beta-amyloid, vascular pathology and inflammation in patients with AD and in animal models
Noscapine Treatment Effect In Transgenic Mouse Model Of Alzheimer'S Disease
- 负责人：
- 关键词：
- Alzheimer's disease Transgenic mouse Magnetic resonance imaging Cerebral vascular reactivity Cerebral blood flow Cerebrovascular dysfunction
- DOI：
- doi:10.5281/zenodo.1209065
- 摘要：
- involving bradykinin receptor has been proposed at the nexus of beta-amyloid, vascular pathology and inflammation in patients with AD and in animal models
Data from: Non-invasive imaging of CSF-mediated brain clearance pathways via assessment of perivascular fluid movement with DTI MRI
- 负责人：
- DOI：
- doi:10.5061/dryad.121hs31
- 摘要：
- The glymphatics system describes a CSF-mediated clearance pathway for the removal of potentially harmful molecules, such as amyloid beta, from
Data from: Intermediate Flortaucipir uptake is associated with A&[beta]-PET & CSF-tau in asymptomatic adults
- 负责人：
- DOI：
- doi:10.5061/dryad.4q4h8q1
- 摘要：
- -AD cohort, mean age=67±5) underwent tau PET ([18F]flortaucipir), ?-amyloid (A?) PET ([18F]NAV4694), and cognitive assessment. A subsample of 74
Dataset for research paper: α-Synuclein Increases β-Amyloid Secretion by Promoting β-\/γ-Secretase Processing of APP
- 负责人：
- University Of Bath
- DOI：
- doi:10.15125/bath-00310
- 摘要：
- PI-1, Amyloid Precursor Protein β-Secretase Inhibitor (βSI), and β-Secretase Inhibitor IV (βIV) were purchased from Merck Millipore. DAPT was purchased from Tocris. TAPI, βSI, βIV
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