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Data from: Mosaic VSGs and the scale of Trypanosoma brucei antigenic variation
负责人:
关键词:
antigenic variation;Parasite;pseudogene;trypanosome;immune evasion;segmental gene conversion;Trypanosoma brucei
DOI:
doi:10.5061/dryad.7pc00
摘要:
acquired immunity and antigenic variation of the parasite variant surface glycoprotein (VSG) coat. About 0.1% of trypanosome divisions produce a switch to a different
Antigenic variation by switching inter-chromosomal interactions with an RNA splicing locus in trypanosomes
负责人:
关键词:
3D genome architecture RNA maturation antigenic variation monoallelic Trypanosoma brucei
DOI:
doi:10.5281/zenodo.3628212
摘要:
and livestock, employ an antigenic variation mechanism that involves monogenic antigen expression from a pool of >2500 antigen-coding genes. In other
Antigenic variation by switching inter-chromosomal interactions with an RNA splicing locus in trypanosomes
负责人:
关键词:
3D genome architecture RNA maturation antigenic variation monoallelic Trypanosoma brucei
DOI:
doi:10.5281/zenodo.3628213
摘要:
and livestock, employ an antigenic variation mechanism that involves monogenic antigen expression from a pool of >2500 antigen-coding genes. In other
Data from: Genome-wide evolutionary dynamics of influenza B viruses on a global scale
负责人:
关键词:
influenza;antigenic drift;phylogenetics;molecular evolution
DOI:
doi:10.5061/dryad.s1d37
摘要:
spread among clades. Differences between the lineages are reflected in their antigenic dynamics, as Yamagata-lineage viruses show alternating dominance bet
Data from: MHC class II diversity of koala (Phascolarctos cinereus) populations across their range
负责人:
关键词:
diversity;koala;positive selection;Phascolarctos cinereus;Inbreeding;MHC class II
DOI:
doi:10.5061/dryad.19856
摘要:
and genetic differentiation using analysis of molecular variance. The higher MHCII diversity in the north relative to south could potentially be attributed to (i) significant
Data from: Phased whole-genome genetic risk in a family quartet using a major allele reference sequence
负责人:
关键词:
DOI:
doi:10.5061/dryad.34q0d
摘要:
and pharmacogenomic risk across the coding and non-coding genome that incorporate phased variant data. We show these methods are capable of identifying multigenic risk
Data from: Global circulation patterns of seasonal influenza viruses vary with antigenic drift
负责人:
关键词:
influenza;Influenzavirus B;Influenzavirus A;influenza virus;phylogenetics;phylogeography
DOI:
doi:10.5061/dryad.pc641
摘要:
in disseminating new variants. The less frequent global movement of influenza A/H1N1 and B viruses coincided with slower rates of antigenic evolution, lower age
Data from: MHC class II DRB diversity predicts antigen recognition and is associated with disease severity in California sea lions naturally infected
负责人:
关键词:
DRB polymorphism;Leptospirosis;California sea lion;Zalophus californianus;Major histocompatibility complex;Antibodies;Holocene;Leptospira
DOI:
doi:10.5061/dryad.7mc93
摘要:
ne sequences are involved with antigen presentation of bacteria and other extracellular pathogens, we predicted that they would play a role in determining responses
Data from: Selected HLA-B allotypes are resistant to inhibition or deficiency of the transporter associated with antigen processing (TAP)
负责人:
关键词:
DOI:
doi:10.5061/dryad.m4862mk
摘要:
Major histocompatibility complex class I (MHC-I) molecules present antigenic peptides to CD8+ T cells, and are also important for natural killer (NK
Data from: Diversity of MHC DQB and DRB genes in the endangered Australian sea lion (Neophoca cinerea)
负责人:
关键词:
Hookworm;MHC;Neophoca cinerea;Pinnipeds;Australian sea lion Subject area: Conservation genetics and biodiversity
DOI:
doi:10.5061/dryad.n4g95
摘要:
ng, and evaluation of diversity in pups across 2 colonies using variant screening (n = 47), 3 DQB alleles and 10 DRB variants (including 1 pseudogene allele) wer

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