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共检索到48条 ,权限内显示50条;
Data from: From cellular characteristics to disease diagnosis: uncovering phenotypes with supercells
- 负责人:
- DOI:
- doi:10.5061/dryad.v6st3
- 摘要:
- lthy and diseased patients, as well as between different diseases that are difficult to diagnose otherwise. We apply our approach to two kinds of single-cell datase
Data from: Transcriptomic alterations during ageing reflect the shift from cancer to degenerative diseases in the elderly
- 负责人:
- DOI:
- doi:10.5061/dryad.4b5n5
- 摘要:
- ciated transcriptomic changes follow trajectories similar to the transcriptional alterations observed in degenerative ageing diseases but are in opposite di
Data from: Revisiting protein aggregation as pathogenic in sporadic Parkinson’s and Alzheimer’s diseases
- 负责人:
- Espay, Alberto J.
- 关键词:
- Parkinson’s disease Alzheimer’s disease biomarkers disease modifying treatments clinical trials
- DOI:
- doi:10.5061/dryad.g1nq02r
- 摘要:
- The gold standard for a definitive diagnosis of Parkinson’s disease (PD) is the pathologic finding of aggregated alpha-synuclein into Lewy bodies
Data from: Early-life inflammation, immune response and ageing
- 负责人:
- DOI:
- doi:10.5061/dryad.dk034
- 摘要:
- Age-related diseases are often attributed to immunopathology, which results in self-damage caused by an inappropriate inflammatory response
Data from: Risk factors for respiratory illness in a community of wild chimpanzees (Pan troglodytes schweinfurthii)
- 负责人:
- 关键词:
- apes;Epidemiology;disease;Pan troglodytes schweinfurthii;health;Aging;human-wildlife interaction
- DOI:
- doi:10.5061/dryad.1m004jc
- 摘要:
- of respiratory illness in the chimpanzees did not track seasonal rates of disease in the nearby village. Our data indicate that the epidemiology of chimpanzee
Data from: Disentangling synergistic disease dynamics: Implications for the viral biocontrol of rabbits
- 负责人:
- Wells, Konstans
- 关键词:
- biocontrol disease transmission epidemiological dynamics host-pathogen interactions invasive species management myxoma virus rabbit haemorrhagic disease virus (RHDV) virulence
- DOI:
- doi:10.5061/dryad.3hd6sb6
- 摘要:
- European rabbits (Oryctolagus cuniculus) have been exposed to rabbit haemorrhagic disease virus (RHDV) and myxoma virus (MYXV) in their native
Data from: Heritability of lifespan is largely sex-limited in Drosophila
- 负责人:
- DOI:
- doi:10.5061/dryad.q412q
- 摘要:
- t integrate over all genetic factors that contribute to mortal disease, it also implies that the genetics of heritable disease differs vastly between the sexes.
Data from: Progressive parkinsonism in older adults is related to the burden of mixed-brain pathologies
- 负责人:
- DOI:
- doi:10.5061/dryad.vn42tj2
- 摘要:
- Objective: To examine if indices of Parkinson’s disease (PD) pathology and other brain pathologies are associated with the progres
Data from: Total A?42/A?40 ratio in plasma predict amyloid-PET status, independent of clinical AD diagnosis
- 负责人:
- DOI:
- doi:10.5061/dryad.f300d56
- 摘要:
- Background: Research has focussed upon the identification of a blood-based biomarker to inform clinicians on the likelihood of Alzheimer’s disease
Data from: Risk factors for possible REM sleep behavior disorder: a CLSA population-based cohort study
- 负责人:
- DOI:
- doi:10.5061/dryad.0k27q21
- 摘要:
- ultimately phenoconverting to defined disease. Several environmental risk factors for RBD have been suggested, but associations vary between studies