Data from: The N-end Rule Pathway and Ubr1 enforce protein compartmentalization via P2-encoded cellular location signals

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关键词：

P2 residue;N-degron;P2;Ubr1;protein quality control;N-end rule;Protein Folding;Saccharomyces cerevisiae;proteolysis

DOI：

doi:10.5061/dryad.r837vv7

摘要：

. However, the root physiological purpose of this activity is not completely understood. Through a systematic examination of single residue P2-posi

Data from: Agonist-specific voltage-dependent gating of lysosomal Two-Pore Na + Channels

负责人：

关键词：

Whole-endolysosome patch-clamp;anti-depressants;lysosomal two-pore channel

DOI：

doi:10.5061/dryad.s5f6j9h

摘要：

, TPC2 lacks such voltage dependence despite the presence of several positively-charged amino acid (AA) residues in the presumed “S4 voltage-sensi