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共检索到29条 ,权限内显示50条;
Data from: Para-aminosalicylic acid acts as an alternative substrate of folate metabolism in Mycobacterium tuberculosis
- 负责人：
- DOI：
- doi:10.5061/dryad.vh36n
- 摘要：
- is assumed to inhibit dihydropteroate synthase (DHPS) in Mycobacterium tuberculosis by mimicking the substrate p-aminobenzoate (PABA). However, we found tha
Data from: Reversion of antibiotic resistance in Mycobacterium tuberculosis by spiroisoxazoline SMARt-420
- 负责人：
- DOI：
- doi:10.5061/dryad.mb463
- 摘要：
- tant Mycobacterium tuberculosis have now spread worldwide. Some key antituberculosis antibiotics are prodrugs, for which resistance mechanisms are mainly driven by mutations
Data from: Release of 50 new, drug-like compounds and their computational target predictions for open source anti-tubercular drug discovery
- 负责人：
- DOI：
- doi:10.5061/dryad.8r351
- 摘要：
- As a follow up to the antimycobacterial screening exercise and the release of GSK?s first Tres Cantos Antimycobacterial Set (TCAMS-TB), this paper pr
Data from: Risk factors associated to a high Mycobacterium tuberculosis complex seroprevalence in wild boar (Sus scrofa) from a low
- 负责人：
- DOI：
- doi:10.5061/dryad.w9ghx3fkp
- 摘要：
- by Mycobacterium bovis, a member of the Mycobacterium tuberculosis complex (MTC). In southern Iberian peninsula, wild reservoirs such as the wild boar, amo
Data from: Construction of a virtual Mycobacterium tuberculosis consensus genome and its application to data from a next generation sequencer
- 负责人：
- 关键词：
- phylogenetic analysis;Mycobacterium tuberculosis;consensus sequence;virtual typing;SNP concatemer
- DOI：
- doi:10.5061/dryad.nq070
- 摘要：
- Background: Although Mycobacterium tuberculosis isolates are consisted of several different lineages and the epidemiology analyses are usua
Data from: Characteristics of patients with smear-negative pulmonary tuberculosis (TB) in a region with high TB and HIV prevalence
- 负责人：
- 关键词：
- Tuberculosis
- DOI：
- doi:10.5061/dryad.fh8hs
- 摘要：
- as having smear-positive pulmonary TB (SPPT). All adult patients (? 18 years old) with a positive culture for Mycobacterium tuberculosis, and a diagnosis
Data from: Efferocytosis and extrusion of leukocytes determine the progression of early mycobacterial pathogenesis
- 负责人：
- DOI：
- doi:10.5061/dryad.08803
- 摘要：
- Mycobacterium marinum infection in the tissue of the larval tail fin. Our results show that neutrophils are efficient in phagocytosis of mycobacteria and tha
Data from: Evaluation of Xpert? MTB/RIF assay in induced sputum and gastric lavage samples from young children with suspected tuberculosis from
- 负责人：
- DOI：
- doi:10.5061/dryad.tt29d
- 摘要：
- collected. 57 of 4,463[1.3%] and 26 of 4,606[0.6%] samples tested positive for Mycobacterium tuberculosis on MGIT culture and Xpert MTB/RIF assay respective
Data from: Performance of TaqMan Array Card to detect TB drug resistance on direct specimens
- 负责人：
- DOI：
- doi:10.5061/dryad.nt615
- 摘要：
- Culture based phenotypic drug susceptibility testing (DST) for Mycobacterium tuberculosis (TB) is time consuming therefore rapid genotypic methods ar
Data from: A chromosome 5q31.1 locus associates with tuberculin skin test reactivity in HIV-positive individuals from tuberculosis hyper-endemic
- 负责人：
- DOI：
- doi:10.5061/dryad.cq183
- 摘要：
- One in three people has been infected with Mycobacterium tuberculosis (MTB), and the risk for MTB infection in HIV-infected individuals is even high
