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Data from: A quantitative proteomic analysis of cofilin phosphorylation in myeloid cells and its modulation using the LIM kinase inhibitor Pyr1
- 负责人：
- DOI：
- doi:10.5061/dryad.4n5929c
- 摘要：
- LIM kinases are located at a strategic crossroad, downstream of several signaling pathways and upstream of effectors such as microtubules
LIM Domain Kinase 1 (LIMK1), Human Kinase Domain; A Target Enabling Package
- 负责人：
- Eidarus Salah;;Beltrami, Alessandra;;Apirat Chaikuad;;Hanke, Thomas;;Kashima, Risa;;Canning, Peter;;Knapp, Susanne Muller;;Knaus, Petra;;Hata, Aki
- DOI：
- doi:10.5287/bodleian:zg5naqjyk
- 摘要：
- ng via the kinase LIMK1. LIMK1 performs inhibitory phosphorylation on cofilin proteins blocking their actin-severing activity. Excessive BMPR2-LIM
Human Lim Domain Kinase 1 (Limk1), Kinase Domain; A Target Enabling Package
- 负责人：
- 关键词：
- protein target enabling package disease structure cancer neuropsychiatry neuro neurological genetic disorders metabolic diseases oncology
- DOI：
- doi:10.5281/zenodo.1287260
- 摘要：
- ng via the kinase LIMK1. LIMK1 performs inhibitory phosphorylation on cofilin proteins blocking their actin-severing activity. Excessive BMPR2-LIM
Human Lim Domain Kinase 1 (Limk1), Kinase Domain; A Target Enabling Package
- 负责人：
- 关键词：
- protein target enabling package disease structure cancer neuropsychiatry neuro neurological genetic disorders metabolic diseases oncology
- DOI：
- doi:10.5281/zenodo.1241027
- 摘要：
- ng via the kinase LIMK1. LIMK1 performs inhibitory phosphorylation on cofilin proteins blocking their actin-severing activity. Excessive BMPR2-LIM
Human LIM domain kinase 1 (LIMK1), kinase domain; A Target Enabling Package
- 负责人：
- 关键词：
- protein target enabling package disease structure cancer neuropsychiatry neuro neurological genetic disorders metabolic diseases oncology
- DOI：
- doi:10.5281/zenodo.1219706
- 摘要：
- ng via the kinase LIMK1. LIMK1 performs inhibitory phosphorylation on cofilin proteins blocking their actin-severing activity. Excessive BMPR2-LIM
Data from: Structure-based network analysis of activation mechanisms in the ErbB family of receptor tyrosine kinases: the regulatory spine residues
- 负责人：
- 关键词：
- protein kinases;protein structure network analysis;structural stability;force constant analysis
- DOI：
- doi:10.5061/dryad.qj597
- 摘要：
- s in the ErbB kinases. We have determined that residues that are indispensable for kinase regulation and catalysis often corresponded to the high centrality nodes
Data from: A highly sensitive LC-MS/MS method to determine novel Bruton's tyrosine kinase inhibitor spebrutinib: application to metabolic stability evaluation
- 负责人：
- DOI：
- doi:10.5061/dryad.5m09t8k
- 摘要：
- Spebrutinib (SBT) is a Bruton's tyrosine kinase inhibitor. SBT is currently in phase II and phase I clinical trials for the management
Data from: Ecological relevance of energy metabolism: transcriptional responses in energy sensing and expenditure to thermal and osmotic stresses
- 负责人：
- DOI：
- doi:10.5061/dryad.6824n
- 摘要：
- high temperature, desiccation and rainfall. Expression levels of genes encoding metabolic regulators [two subunits of AMP-activated protein kinase, ampk?, ampk?; Fu
Data from: Dissecting nutrient-related co-expression networks in phosphate starved poplars
- 负责人：
- DOI：
- doi:10.5061/dryad.3t5q5
- 摘要：
- in the plant. In this module the GO term “response to P starvation” was enriched with phosphoenolpyruvate carboxylase kinases, phosphatases and pyrophosphatases
Data from: Dopamine promotes motor cortex plasticity and motor skill learning via PLC activation
- 负责人：
- DOI：
- doi:10.5061/dryad.mp5s3
- 摘要：
- ferent G-proteins and bidirectionally modulate protein kinase A (PKA), leading to distinct physiological and behavioral effects. Here we show that D1
