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Data from: Evaluating in vitro-in vivo extrapolation of toxicokinetics
- 负责人：
- DOI：
- doi:10.5061/dryad.32v7b
- 摘要：
- , which are often unavailable. Relatively high throughput, in vitro TK (HTTK) assays and in vitro-to-in vivo extrapolation (IVIVE) methods hav
Data from: Quantification of the activity of detoxifying enzymes in terrestrial invertebrates: optimization, evaluation and use of in vitro
- 负责人：
- DOI：
- doi:10.5061/dryad.48hg077
- 摘要：
- , Tenebrio molitor was used to illustrate why in vitro methods are ineffective to quantify metabolic enzymes in some insects. It was further used to optimize
Data from: Cavin-3 dictates the balance between ERK and Akt signaling
- 负责人：
- DOI：
- doi:10.5061/dryad.4950k
- 摘要：
- Cavin-3 is a tumor suppressor protein of unknown function. Using a combination of in vivo knockout and in vitro gain/loss of function appro
Data from: In-vitro cultivation of liveforevers (genus Dudleya) to reduce poaching and extinction
- 负责人：
- 关键词：
- DOI：
- doi:10.7280/D1NH4W
- 摘要：
- st, I compared the propagation of in-vitro and ex-vitro grown seeds to understand if in-vitro culture enhances germination, survival, and growth. Se
Data from: Phage resistance evolution in vitro is not reflective of in vivo outcome in a plant-bacteria-phage system
- 负责人：
- DOI：
- doi:10.5061/dryad.v3r5d21
- 摘要：
- of resistance evolution in vitro. We find no evidence supporting the evolution of phage resistance in planta despite multiple passaging experiments, multiple assays
Data from: Individuals with higher metabolic rates have lower levels of reactive oxygen species hydrogen peroxide in vivo
- 负责人：
- DOI：
- doi:10.5061/dryad.t5c10
- 摘要：
- indirectly from measurements in vitro, which may not reflect actual ROS production in living animals. Here, we measured in vivo H2O2 content using the recent
Data from: DNA methylation and gene expression changes derived from assisted reproductive technologies can be decreased by reproductive fluids
- 负责人：
- 关键词：
- DOI：
- doi:10.5061/dryad.n77r3
- 摘要：
- from single pig blastocysts showing differences between in vivo and in vitro produced embryos. Blastocysts were produced in vitro either without (C-IVF
Data from: Soft-surface grasping: radular opening in Aplysia californica
- 负责人：
- Chiel, Hillel J.
- DOI：
- doi:10.5061/dryad.56r18rv
- 摘要：
- . Previous in vitro studies suggested that an intrinsic muscle, I7, is responsible for opening the radula. Lesioning I7 in vivo does reduce opening width
Data from: Using long-term experimental evolution to uncover the patterns and determinants of molecular evolution of an Escherichia coli natural
- 负责人：
- 关键词：
- gut colonization mouse model;Experimental evolution;Escherichia coli;536;streptomycin resistance
- DOI：
- doi:10.5061/dryad.4g503
- 摘要：
- bial adaptation in the gut. Experimental evolution coupled with whole genome sequencing can provide insights of the adaptive process. In vitro experiments have revealed som
Data from: Identification of reactive intermediate formation and bioactivation pathways in Abemaciclib metabolism by LC–MS/MS: in vitro metabolic
- 负责人：
- DOI：
- doi:10.5061/dryad.71f1s18
- 摘要：
- Abemaciclib (Verzenio?) is approved as tyrosine kinase inhibitor (TKI) for breast cancer treatment. In this study, in vitro phase I
