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Data from: Collagen vitrigel promotes hepatocytic differentiation of induced pluripotent stem cells into functional hepatocyte-like cells
- 负责人：
- 关键词：
- Homo Sapiens;hepatocytic differentiation;in vitro differentiation;induced pluripotent stem cells
- DOI：
- doi:10.5061/dryad.5f3s52r
- 摘要：
- for at least 2 weeks. Gene array profiling analysis revealed that hiPS cell-derived hepatocyte-like cells (hiPS-hep) resemble that of the primary hepatocytes
Data from: Hepatocyte-specific deletion of TIPARP, a negative regulator of the aryl hydrocarbon receptor, is sufficient to increase sensitivity
- 负责人：
- 关键词：
- DOI：
- doi:10.5061/dryad.qd7t1s8
- 摘要：
- , steatohepatitis, and a lethal wasting syndrome in laboratory rodents. Although the mechanisms of dioxin toxicity remain unknown, AHR signaling in hepatocytes is neces
Data from: Polycyclic aromatic hydrocarbons can trigger hepatocyte release of extracellular vesicles by various mechanisms of action depending
- 负责人：
- DOI：
- doi:10.5061/dryad.3n39r6k
- 摘要：
- contaminants, on hepatocyte-derived EV production, with a special focus on hepatocyte death. Three PAHs were selected, based on their presence in food and thei
Data from: Genome-scale characterization of toxicity-induced metabolic alterations in primary hepatocytes
- 负责人：
- 关键词：
- DOI：
- doi:10.5061/dryad.04vk390
- 摘要：
- of physiological detail. Here, we use transcriptomics data from chemically exposed rat hepatocytes to constrain a GENRE of rat hepatocyte metabolism and predict
Data from: Identification of biomarkers for Barcelona Clinic Liver Cancer staging and overall survival of patients with hepatocellular carcinoma
- 负责人：
- DOI：
- doi:10.5061/dryad.10m4k6q
- 摘要：
- of patients with hepatocellular carcinoma (HCC). We downloaded 4 gene expression datasets from the Gene Expression Omnibus database (http://www.ncbi.nlm.nih.gov
hepatocyte differentiation
- 负责人：
- DOI：
- doi:10.5061/dryad.62gj0
- 摘要：
- is required for post-natal hepatocyte maturation. TAF4 promotes pre-initiation complex (PIC) formation at post-natal expressed liver function genes
Data from: Untargeted metabolomic profiling of urine from healthy dogs and dogs with chronic hepatic disease
- 负责人：
- DOI：
- doi:10.5061/dryad.8dg7kg5
- 摘要：
- urine samples from 10 healthy dogs, 10 dogs with chronic hepatitis, 6 dogs with hepatocellular carcinoma, and 5 dogs with a congenital portosystemic shunt wer
Data from: Dynamically prognosticating patients with hepatocellular carcinoma through survival paths mapping based on time-series data
- 负责人：
- DOI：
- doi:10.5061/dryad.pd44k8r
- 摘要：
- Patients with hepatocellular carcinoma (HCC) always require routine surveillance and repeated treatment, which leads to accumulation of huge amount
Hepatitis B virus X protein regulation of β-catenin and NANOG and co-regulatory role with YAP1 in HCC malignancy
- 负责人：
- 关键词：
- Molecular Microbiology and Immunology hepatocellular carcinoma HCC hepatitis B virus X protein HBx NANOG YAP1 β-catenin tumor initiating cells TICs
- DOI：
- doi:10.25549/usctheses-c3-615884
- 摘要：
- Hepatocellular carcinoma (HCC) is the fifth most common type of cancer. The mortality rate continues to rise every year. Hepat
Data from: From the cover: three-dimensional (3d) heparg spheroid model with physiologically relevant xenobiotic metabolism competence and hepatocyte
- 负责人：
- 关键词：
- DOI：
- doi:10.5061/dryad.s05v3
- 摘要：
- pharmacologically- and environmentally important hepatic receptor pathways (ie AhR, CAR, and PXR) analogous to primary human hepatocyte cultures. HepaRG spheroid
