Data from: Reprogramming the antigen specificity of B cells using genome-editing technologies

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关键词：

HIV broadly neutralizing antibodies;PG9;HIV vaccine;HIV bnAbs genome editing;B cells;antibody repertoire

DOI：

doi:10.5061/dryad.45j0r70

摘要：

) variable region in B cell lines with that from an HIV broadly neutralizing antibody, PG9. Our strategy is designed to function in cells that have undergone VDJ

Data from: Consistency of VDJ rearrangement and substitution parameters enables accurate B cell receptor sequence annotation

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关键词：

B cell maturation;antibody;immunoglobulin;hidden Markov model

DOI：

doi:10.5061/dryad.149m8

摘要：

, in particular for broadly-neutralizing antibodies against HIV and influenza. A fundamental step in such sequence analysis is to annotate each base

Data from: A relaxed directional random walk model for phylogenetic trait evolution

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关键词：

Diffusion Processes;phylogeography;phylogenetics;Phylodynamics;Brownian motion;trait evolution

DOI：

doi:10.5061/dryad.v43rd

摘要：

ext of HIV-1 resistance to three broadly neutralizing antibodies. Our analysis reveals evidence of a continuous drift at the HIV-1 population level towards

Data from: Differentiating founder and chronic HIV envelope sequences

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关键词：

HIV;operations research;envelope sequences

DOI：

doi:10.5061/dryad.r19c2

摘要：

Significant progress has been made in characterizing broadly neutralizing antibodies against the HIV envelope glycoprotein Env, but an effecti