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Data from: Functional diversity and structural disorder in the human ubiquitination pathway
- 负责人:
- 关键词:
- DOI:
- doi:10.5061/dryad.84kj5
- 摘要:
- of increasing complexity, with two E1 (ubiquitin activating), few dozen E2 (ubiquitin conjugating) and several hundred E3 (ubiquitin ligase) enzymes
Data from: The UBR-1 ubiquitin ligase regulates glutamate metabolism to generate coordinated motor pattern in Caenorhabditis elegans
- 负责人:
- Zhen, Mei
- DOI:
- doi:10.5061/dryad.4h49qg1
- 摘要:
- UBR1 is an E3 ubiquitin ligase best known for its ability to target protein degradation by the N-end rule. The physiological functions of UBR
Data from: A genomic survey of HECT ubiquitin ligases in eukaryotes reveals independent expansions of the HECT system in several lineages.
- 负责人:
- 关键词:
- DOI:
- doi:10.5061/dryad.mt620
- 摘要:
- r, studies on the evolutionary history of the proteins involved in this pathway have been restricted to E1 and E2 enzymes, while E3 studies have been focused
The E3-ubiquitin ligase adaptor protein Skp1 is glycosylated by an evolutionarily conserved pathway that regulates protist growth and development.pdf
- 负责人:
- 关键词:
- 60102 Bioinformatics Cell Biology Microbiology Parasitology 60307 Host-Parasite Interactions 60502 Infectious Agents 110309 Infectious Diseases Pathology 60411 Population, Ecological and Evolutionary Genetics 60109 Proteomics and Intermolecular Interactions (excl. Medical Proteomics)
- DOI:
- doi:10.6084/m9.figshare.5505661.v1
- 摘要:
- ecially at low O2. We also observed that Pro154 of Skp1, a subunit of the Skp1/Cullin-1/F-box protein (SCF)-class of E3-ubiquitin ligases, is a natural substrate
Data from: The E3 ubiquitin ligase MARCH1 regulates glucose-tolerance and lipid storage in a sex-specific manner
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- 关键词:
- DOI:
- doi:10.5061/dryad.r34k1
- 摘要:
- , obesity and type 2 diabetes are characterized by chronic low-grade inflammation. Membrane-associated RING-CH-1 (MARCH1) is an E3 ubiquitin ligase best
Data from: Evidence for parallel evolution of a gene involved in the regulation of spermatogenesis
- 负责人:
- DOI:
- doi:10.5061/dryad.m7j5p
- 摘要:
- eas the closely related G2/M-phase specific E3 ubiquitin protein ligase (G2e3) is in the genome of most metazoans. Interestingly, phylogenetic analyses
Data from: Computational and experimental characterization of dVHL establish a Drosophila model of VHL syndrome
- 负责人:
- DOI:
- doi:10.5061/dryad.14pp7
- 摘要:
- s in oxygen availability as part of an E3-ligase that targets the Hypoxia-Inducible Factor for degradation. pVHL has a molten globule configuration with marginal
Data from: The N-end Rule Pathway and Ubr1 enforce protein compartmentalization via P2-encoded cellular location signals
- 负责人:
- DOI:
- doi:10.5061/dryad.r837vv7
- 摘要:
- The Arg/N-end Rule Pathway and Ubr1, an E3 ligase conserved from yeast to humans, is involved in the degradation of misfolded proteins in the cytosol
The Population\u2019s Labour Force Participation at the Federal Republic of Germany (FRG) between 1950 and 1997
- 负责人:
- DOI:
- doi:10.4232/1.8184
- 摘要:
- ?nder, Deutschland (1957-2000) E3 Revidierte Ergebnisse nach dem ESVG95 E3.1 Erwerbst?tige nach Wirtschaftsbereichen in Tausend, Inlandskonzept (ESVG 1995
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