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Data from: Topological DNA-binding of SMC-like RecN promotes RecA-mediated DNA double-strand break repair
- 负责人:
- DOI:
- doi:10.5061/dryad.7p3p8j3
- 摘要:
- of DNA double-strand breaks (DSBs) by homologous recombination. However, the understanding of how RecN acts in concert with the RecA recombinase to promote DSB repair remains
Data from: Rev7 and 53BP1/Crb2 prevent RecQ helicase-dependent hyper-resection of DNA double-strand breaks
- 负责人:
- 关键词:
- live-cell microscopy;end resection;Schizosaccharomyces pombe;DNA repair;DNA double-strand break
- DOI:
- doi:10.5061/dryad.1db5500
- 摘要:
- Poly(ADP ribose) polymerase inhibitors (PARPi) target cancer cells deficient in homology-directed repair of DNA double-strand breaks (DSBs
Data from: Increased sensitivity of DNA damage response-deficient cells to stimulated microgravity-induced DNA lesions
- 负责人:
- DOI:
- doi:10.5061/dryad.3vc83
- 摘要:
- wild type cells in this study. We observed significant SMG-induced DNA double strand breaks (DSBs) in Rad9-/- MES and Mdc1-/- MEF cells but not in thei
Data from: Sequence analysis of European maize inbred line F2 provides new insights into molecular and chromosomal characteristics of presence
- 负责人:
- Joets, Johann
- DOI:
- doi:10.5061/dryad.f81sj
- 摘要:
- of double strand break repair, but also transposon insertion in PAV generation. Typing of the B73 and F2 PAVs in maize temperate inbreds revealed that some PAVs ar
Data from: High throughput sequencing reveals alterations in the recombination signatures with diminishing spo11 activity
- 负责人:
- DOI:
- doi:10.5061/dryad.53t4c
- 摘要:
- Spo11 is the topoisomerase-like enzyme responsible for the induction of the meiosis-specific double strand breaks (DSBs), which initiate
Data from: Controlling meiotic recombinational repair: specifying the roles of ZMMs, Sgs1 and Mus81/Mms4 in crossover formation
- 负责人:
- DOI:
- doi:10.5061/dryad.79hn1
- 摘要:
- t multiple events do not arise from a single double-strand break (DSB). Here, by interpreting signatures that result from recombination genome-wide
Data from: Fine-Scale Mapping of Recombination Rate in Drosophila Refines its Correlation to Diversity and Divergence
- 负责人:
- DOI:
- doi:10.5061/dryad.484
- 摘要:
- t it is not cross-overs per se that are mutagenic, but rather repair of DNA double-strand break precursors via crossing over and gene conversion.
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