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Data from: Topological DNA-binding of SMC-like RecN promotes RecA-mediated DNA double-strand break repair
- 负责人:
- DOI:
- doi:10.5061/dryad.7p3p8j3
- 摘要:
- of DNA double-strand breaks (DSBs) by homologous recombination. However, the understanding of how RecN acts in concert with the RecA recombinase to promote DSB repair remai

Data from: Controlling meiotic recombinational repair: specifying the roles of ZMMs, Sgs1 and Mus81/Mms4 in crossover formation
- 负责人:
- DOI:
- doi:10.5061/dryad.79hn1
- 摘要:
- recombination between CO vs. noncrossover (NCO) outcomes is not completely understood. Further lacking is what constrains the extent of DNA repair such tha

Data from: High throughput functional genomics identifies modulators of TCE metabolite genotoxicity and candidate susceptibility genes
- 负责人:
- DOI:
- doi:10.5061/dryad.p8k18
- 摘要:
- confirmed by functional profiling in DT40 avian cell lines, but also revealed that translesion synthesis and homologous recombination DNA repair likely play

Data from: Differential requirements for the RAD51 paralogs in genome repair and maintenance in human cells
- 负责人:
- DOI:
- doi:10.5061/dryad.7qj23gr
- 摘要:
- defects, impaired sister chromatid recombination, reduced levels of stable RAD51 nuclear foci, and hyper-sensitivity to mitomycin C and olaparib. Altogether

Data from: Dodging silver bullets: good CRISPR gene-drive design is critical for eradicating exotic vertebrates
- 负责人:
- Prowse, Thomas
- 关键词:
- gene drive homing non-homologous end joining resistance allele population eradication island conservation
- DOI:
- doi:10.5061/dryad.t78gv
- 摘要:
- a homologous recombination. However, their efficacy for controlling wild populations is threatened by inherent polymorphic resistance and the creation of resistance alleles vi

Data from: Genome-wide inference of somatic translocation events during potato dihaploid production
- 负责人:
- 关键词:
- DOI:
- doi:10.5061/dryad.s027503
- 摘要:
- n. The translocations likely result as a consequence of double-stranded break repair in the dihaploid genomes via homologous recombination during which IVP chromosomes ar
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