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Data from: Genetic mapping of novel loci affecting canine blood phenotypes
- 负责人:
- DOI:
- doi:10.5061/dryad.30c8p
- 摘要:
- for disease studies. For many of these dogs, additional clinical phenotypes are available, such as hematological and clinical chemistry results collected duri
Data from: Fadraciclib (CYC065), a novel CDK inhibitor, targets key pro-survival and oncogenic pathways in cancer
- 负责人:
- 关键词:
- DOI:
- doi:10.5061/dryad.44j0zpc9v
- 摘要:
- and pro-survival proteins, including CDK2 and CDK9, have entered clinical development. Here, we provide the first disclosure of the chemical str
\u2022\tRegulatory requirement for drug development and approval in United States: review
- 负责人:
- 关键词:
- 111701 Aboriginal and Torres Strait Islander Health 111001 Aged Care Nursing 111702 Aged Health Care 110301 Anaesthesiology 110901 Autonomic Nervous System 111501 Basic Pharmacology Biomarkers 110601 Biomechanics 111201 Cancer Cell Biology 111202 Cancer Diagnosis
- DOI:
- doi:10.6084/m9.figshare.3381274.v1
- 摘要:
- involving drugdiscovery, laboratory development, animal studies, clinicaltrials, and regulatory registration. This lengthy process isnecessary to assure
Data from: Development and evaluation of a fluorescent antibody-drug conjugate for molecular imaging and targeted therapy of pancreatic cancer
- 负责人:
- DOI:
- doi:10.5061/dryad.6j018
- 摘要:
- d for targeted therapy, immunohistochemical staining, or in vivo diagnostic imaging of cancer. Significant advances in site-specific antibody labeling technologies hav
Data from: Whole transcriptome RNA-Seq analysis of breast cancer recurrence risk using formalin-fixed paraffin-embedded tumor tissue
- 负责人:
- DOI:
- doi:10.5061/dryad.q760h
- 摘要:
- e developed and optimized RNA-Seq library chemistry as well as bioinformatics and biostatistical methods for whole transcriptome profiling from FFPE tissue
Data from: Metabolite profile of a mouse model of Charcot-Marie-Tooth type 2D neuropathy: implications for disease mechanisms and interventions
- 负责人:
- Burgess, Robert W.
- DOI:
- doi:10.5061/dryad.ng07t
- 摘要:
- dated using clinical blood chemistry. These effects were not secondary to the neuromuscular phenotype, as determined by comparison with another, genetical
Data from: A novel open access web portal for integrating mechanistic and toxicogenomic study results
- 负责人:
- DOI:
- doi:10.5061/dryad.159h65k
- 摘要:
- que feature of the software is the ability to integrate clinical chemistry and histopathology-derived outcomes with results from gene expression studies
Identification of small-molecules targeting CXCR2 function and signaling
- 负责人:
- DOI:
- doi:10.25549/usctheses-c3-308809
- 摘要:
- inhibitors are limited to four major chemical classes of compounds and are by far scarce compared to other clinically relevant therapeutic
Data from: Plasma pro-atrial natriuretic peptide to indicate fluid balance during cystectomy: a prospective observational study
- 负责人:
- DOI:
- doi:10.5061/dryad.116js
- 摘要:
- university/tertiary centre. Participants: The study included patients who underwent radical cystectomy. Plasma for determination of proANP was obtaine
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