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Data from: A crystal structure of a collaborative RNA regulatory complex reveals mechanisms to refine target specificity
负责人:
关键词:
Caenorhabditis elegans
DOI:
doi:10.5061/dryad.30501q7
摘要:
-2 binding affinity for short and long motifs, which may increase target selectivity. Our findings highlight the role of FBF scaffold flexibility in RNA recogniti
Data from: Discovery and information-theoretic characterization of transcription factor binding sites that act cooperatively
负责人:
关键词:
Drosophila;mutual information;Transcription Factor Binding Sites;Position Weight Matrix
DOI:
doi:10.5061/dryad.8b203
摘要:
lity of a DNA binding site sequence by assuming positional independence within the DNA sequence. Here we construct conditional PWMs that depend on the motif signatures
Data from: Global pairwise RNA interaction landscapes reveal core features of protein recognition
负责人:
关键词:
SEQRS;Global landscapes;DCA;specificity;molecular recognition;Protein-RNA
DOI:
doi:10.5061/dryad.qs734tp
摘要:
by RNA-binding proteins. Models of RNA–protein interactions are generally limited to short linear motifs and structures because of the vast sequence sampling required
Data from: Measuring NDC80 binding reveals the molecular basis of tension-dependent kinetochore-microtubule attachments
负责人:
关键词:
Homo Sapiens
DOI:
doi:10.5061/dryad.14rr125
摘要:
of the NDC80 complex, and the proper localization of Aurora B kinase, which modulates NDC80 binding. Our results lead to a mathematical model of the molecular basis
Data from: Positive selection in coding regions and motif duplication in regulatory regions of bottlenose dolphin MHC class II genes
负责人:
关键词:
Major histocompatibility complex;DQB;DQA;peptide binding region;promoter;Tursiops truncatus
DOI:
doi:10.5061/dryad.r36sg
摘要:
on sequencing methodology to characterize coding (peptide binding region) and regulatory (proximal promoter) sequence variation in MHC Class II DQA and DQB genes bet
Data from: Antennal transcriptome analysis and expression profiles of odorant binding proteins in Eogystia hippophaecolus (Lepidoptera: Cossidae)
负责人:
关键词:
Expression profile;transcriptome;Eogystia hippophaecolus;Olfactory proteins
DOI:
doi:10.5061/dryad.2dj50
摘要:
control method. Results: We identified 29 transcripts encoding putative odorant-binding proteins (OBPs), 18 putative chemosensory proteins (CSPs), 63 odorant receptors
are global mediators of structural stability and allosteric interactions
负责人:
关键词:
protein kinases;protein structure network analysis;structural stability;force constant analysis
DOI:
doi:10.5061/dryad.qj597
摘要:
t kinase activation may be determined by allosteric interactions between modules of structurally stable residues that synchronize the dynamics in the nucleotide binding
Data from: Calcium imaging with genetically encoded sensor Case12: facile analysis of ?7/?9 nAChR mutants
负责人:
关键词:
Naja kaouthia;Xenopus laevis
DOI:
doi:10.5061/dryad.4k831
摘要:
and fast desensitization. Here, we probed the ligand-binding properties of ?7/?9 nAChR mutants by a proposed simple and fast calcium imaging method
Data from: Diversity of opisthokont septin proteins reveals structural constraints and conserved motifs
负责人:
Auxier, Ben
关键词:
DOI:
doi:10.5061/dryad.2b1r2sh
摘要:
were responsible for subunit binding specificity. Results: Here we take advantage of newly sequenced genomes to reconcile septi
Data from: Structural and mechanistic basis of zinc regulation across the E. coli Zur regulon
负责人:
关键词:
Escherichia coli
DOI:
doi:10.5061/dryad.vn6dv
摘要:
cooperative binding of two adjacent dimers to essentially encircle the core element of each of the Zur-regulated promoters. Cooperativity in these protein-DNA interacti

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