Data from: Peripheral synucleinopathy in a DJ1 patient with Parkinson disease, cataracts, and hearing loss

负责人：

关键词：

Movement Disorders;synuclein;Neuro-ophthalmology;Parkinson's disease\/Parkinsonism;Parkin

DOI：

doi:10.5061/dryad.nv892mp

摘要：

, in which atypical clinical features are usually absent, and, in contrast to idiopathic PD, synucleinopathy is lacking and olfaction preserved.2 Whether DJ1

Dataset for research paper: α-Synuclein Increases β-Amyloid Secretion by Promoting β-\/γ-Secretase Processing of APP

负责人：

University Of Bath

关键词：

Biochemistry and physiology Cells

DOI：

doi:10.15125/bath-00310

摘要：

, and DAPT were made up as 1000x concentrated stocks in DMSO (Sigma).\r\rDNA Constructs\rPlasmids encoding wildtype α-synuclein (RefSeq accession number XM

Data from: Exogenous ?-synuclein hinders synaptic communication in cultured cortical primary rat neurons

负责人：

关键词：

Multi-electrode aray;In vitro cultured neurons;Parkinsons disease;alpha synuclein

DOI：

doi:10.5061/dryad.m7fk370

摘要：

Amyloid aggregates of the protein ?-synuclein (?S) called Lewy Bodies (LB) and Lewy Neurites (LN) are the pathological hallmark

Data from: Gut microbiota regulate motor deficits and neuroinflammation in a model of Parkinson’s disease

负责人：

Mazmanian, Sarkis K.

关键词：

synuclein microbiome Parkinson’s disease gut-brain axis mouse model microglia short chain fatty acids

DOI：

doi:10.5061/dryad.4mp6h

摘要：

ween gut bacteria and neurodegenerative diseases remains unexplored. Synucleinopathies are characterized by aggregation of the protein α-synuclein (αSyn), often res

Data from: Revisiting protein aggregation as pathogenic in sporadic Parkinson’s and Alzheimer’s diseases

负责人：

Espay, Alberto J.

关键词：

Parkinson’s disease Alzheimer’s disease biomarkers disease modifying treatments clinical trials

DOI：

doi:10.5061/dryad.g1nq02r

摘要：

The gold standard for a definitive diagnosis of Parkinson’s disease (PD) is the pathologic finding of aggregated alpha-synuclein into Lewy bodies

Data from: Association between restless legs syndrome and other movement disorders

负责人：

关键词：

Parkinsonism;Restless legs syndrome;Ataxia;Tourette syndrome;Essential tremor;Movement Disorders

DOI：

doi:10.5061/dryad.7qm13nn

摘要：

ween Parkinson’s disease and RLS (the presence of allele 2 of the complex microsatellite repeat Rep1 within the alpha-synuclein gene promoter) and between Tourette