Identification of small-molecules targeting CXCR2 function and signaling

负责人：

关键词：

CXCL8 Pharmaceutical Sciences CXCR2 inflammation

DOI：

doi:10.25549/usctheses-c3-308809

摘要：

using a cell-based cyclic AMP assay. CX797 inhibited the effects of CXCL8 on forskolin-induced cyclic AMP signaling, while enhancing CXCR2/β-arrestin2

Data from: Chronic household air pollution exposure is associated with impaired alveolar macrophage function in Malawian non-smokers

负责人：

关键词：

pneumonia;Alveolar macrophage;Indoor air pollution

DOI：

doi:10.5061/dryad.89nj3

摘要：

and proteolytic function were unaffected. High particulate content was associated with lower baseline CXCL8 release (ratio 0.51, CI 0.29–0.89) and lower final

Data from: Immunomodulatory effects of tick saliva on dermal cells exposed to Borrelia burgdorferi, the agent of Lyme disease

负责人：

关键词：

DNA microarray;Lyme disease;Borrelia burgdorferi;Tick saliva;cytokines;Monocyte\/Macrophages;Fibroblasts;Homo Sapiens;Macaca mulatta;Chemokines

DOI：

doi:10.5061/dryad.s1bg6

摘要：

t on the expression of certain pro-inflammatory mediators, such as IL-8 (CXCL8) and TLR2, but had a stimulatory effect on specific molecules such as the Interleukin 10