The Trustees of Columbia University in the City of New York
发明人:
Donald W. LANDRY,Shi-Xian DENG,Xiaoming XU,Thomas DIACOVO
申请号:
US16633074
公开号:
US20200165211A1
申请日:
2018.07.31
申请国别(地区):
US
年份:
2020
代理人:
摘要:
In an aspect, the disclosure provides for compounds (II), compositions, and methods of administering the compounds and compositions to a patient in need thereof. In another aspect, the disclosure relates to compounds and compositions for treating cancer, for example, lymphoid leukemia. The disclosure further provides for compounds which inhibit two phosphoinositide 3-kinase (PI3K) isoforms, y and δ, pharmaceutical compositions comprising said compounds, and methods of using said compounds and pharmaceutical compositions for treatment, amelioration, and/or prevention of non-Hodgkin lymphoma.