Innovative indanesulfamide derivative

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专利权人:

Ltd.;Eisai R&D Management Co.

发明人:

申请号：

ES13807707

公开号：

ES2628374T3

申请日:

2013.06.17

申请国别(地区):

ES

年份:

2017

代理人:

摘要：

A compound or a pharmaceutically acceptable salt thereof, which is selected from the group: 1) N - [(1 S) -2,2,5,7-tetrafluoro-2,3-dihydro-1H-inden-1-yl] sulfamide, 2) N - [(1S) -2,2,4,7-tetrafluoro-2,3-dihydro-1H-inden-1-yl] sulfamide, 3) (+) - N- (2,2, 4,6,7-pentafluoro-2,3-dihydro-1H-inden-1-yl) sulfamide, 4) N - [(1S *) - 5-cyano-2,2-difluoro-7-methyl-2, 3-dihydro-1H-inden-1-yl] sulfamide, 5) (-) - N- (7-chloro-2,2,5-trifluoro-2,3-dihydro-1H-inden-1-yl) sulfamide , 6) (-) - N- (7-chloro-2,2,4-trifluoro-2,3-dihydro-1H-inden-1-yl) sulfamide, 7) (-) - N- (7-chloro -2,2-difluoro-2,3-dihydro-1H-inden-1-yl) sulfamide, 8) (-) - N- (7-chloro-2,2,6-trifluoro-2,3-dihydro- 1H-inden-1-yl) sulfamide, 9) (+) - N- (5-chloro-2,2,7-trifluoro-2,3-dihydro-1H-inden-1-yl) sulfamide, 10) N - [(1S) -2,2-Difluoro-7-methyl-2,3-dihydro-1H-inden-1-yl] sulfamide, 11) N - [(1S) -2,2,5-trifluoro-7 -methyl-2,3-dihydro-1H-inden-1-yl] sulfamide, 12) N - [(1S *) - 2,2,4-trifluoro-7-methyl-2,3-dihydro-1H-inden -1-yl] sulfamide, 13) N - [(1S *) - 7- (difluoromethyl) -2,2-difluoro-2,3-dih idro-1H-inden-1-yl] sulfamide, 14) N - [(1R *, 2R *) - 2,4,7-trifluoro-2,3-dihydro-1H-inden-1-yl] sulfamide, 15 ) (-) - N - [(1R *, 2R *) - 7-Chloro-2,4-difluoro-2,3-dihydro-1H-inden-1-yl] sulfamide, 16) (+) - N- [(1R *, 2R *) - 7-Chloro-2,4-difluoro-2,3-dihydro-1H-inden-1-yl] sulfamide, 17) (-) - N - [(1R *, 2R * ) -7-Chloro-2,5-difluoro-2,3-dihydro-1H-inden-1-yl] sulfamide, 18) (+) - N - [(1R *, 2R *) - 4-Chloro-7 -fluoro-2-methoxy-2,3-dihydro-1H-inden-1-yl] sulfamide, 19) (+) - N- (7-chloro-4-fluoro-2,3-dihydro-1H-inden- 1-yl) sulfamide, 20) (±) -N- (5-fluoro-7-methyl-2,3-dihydro-1H-inden-1-yl) sulfamide, 21) (-) - N- (4- fluoro-7-methyl-2,3-dihydro-1H-inden-1-yl) sulfamide, 22) (+) - N- (4-fluoro-7-methyl-2,3-dihydro-1H-inden-1 -yl) sulfamide, 23) (+) - N- (7-methyl-2,3-dihydro-1H-inden-1-yl) sulfamide, 24) (±) -N- (5-chloro-7-methyl -2,3-dihydro-1H-inden-1-yl) sulfamide, 25) (-) - N- (4-chloro-7-fluoro-2,3-di

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