SANTRA, Ramkinkar,BHOGALA, Bala Krishna Reddy,KHANDURI, Chandra, Has
申请号：
IBIB2016/053042
公开号：
WO2016/189463A1
申请日:
2016.05.24
申请国别(地区):
WO
年份:
2016
代理人:
摘要：
The present invention relates to processes for the preparation of an ertugliflozin-L- pyroglutamic acid (1:1) and co-crystal ertugliflozin-L-proline (1:1) co-crystal. The present invention further relates to an ertugliflozin-L-proline (1:2) co-crystal, processes for its preparation, and its use for the treatment of type 2 diabetes mellitus.La présente invention concerne des procédés pour la préparation dun co-cristal dacide ertugliflozin-L-pyroglutamique (1 : 1) et dun co-cristal dertugliflozin-L-proline (1 : 1). Linvention concerne en outre un co-cristal dertugliflozin-L-proline (1:2), ses procédés de préparation, et son utilisation pour le traitement du diabète de type 2.
