Tim Luetkens,Djordje Atanackovic,Sabarinath Venniyil Radhakrishnan
申请号：
US16319386
公开号：
US20190330338A1
申请日:
2017.07.19
申请国别(地区):
US
年份:
2019
代理人:
摘要：
Disclosed are chimeric antigen receptor (CAR) polypeptides comprising a CD229 antigen binding domain, a transmembrane domain, and an intracellular signaling domain. Disclosed are nucleic acid sequences capable of encoding a CAR polypeptide comprising a CD229 antigen binding domain, a transmembrane domain, and an intracellular signaling domain. Also disclosed are vectors and cells comprising one or both of the CAR polypeptides and nucleic acid sequences capable of encoding CAR polypeptides. Also disclosed are methods of treating.
