NOVEL PHARMACEUTICAL USES

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专利权人:

TAKEDA PHARMACEUTICAL COMPANY LIMITED

发明人:

Richard JENKINS,Mark HIBBERD

申请号：

US15563417

公开号：

US20180085361A1

申请日:

2016.03.30

申请国别(地区):

US

年份:

2018

代理人:

摘要：

The invention provides a potassium-competitive acid blocker (P-CAB) for use in the treatment, prevention and/or reduction of gastro-esophageal reflux disease (GERD) symptoms in patients who are partial responders to a proton pump inhibitor (PPI). The P-CAB may, for example, be selected from 1-[5-(2-fluorophenyl)-1-(pyridin-3-ylsulfonyl)-1H-pyrrol-3-yl]-N-methylmethanamine (vonoprazan), revaprazan (YH1855), YH4808, RQ-4 and CS-526, or a salt thereof.

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/