Xiao Min SCHEBYE,Mark J. SELBY,Michelle Minhua HAN,Christine BEE,Andy X. DENG,Anan CHUNTHARAPAI,Brigitte DEVAUX,Huiming LI,Paul O. SHEPPARD,Alan J. KORMAN,Daniel F. ARDOUREL,Ekaterina DEYANOVA,Richard
申请号：
US16697653
公开号：
US20200190186A1
申请日:
2019.11.27
申请国别(地区):
US
年份:
2020
代理人:
摘要：
Provided herein are antibodies, or antigen-binding portions thereof, that bind to T-cell immunoglobulin and mucin-domain containing-3 (TIM3) protein. Also provided are uses of these antibodies, or antigen-binding portions thereof, in therapeutic applications, such as treatment of cancer. Further provided are cells that produce the antibodies, or antigen-binding portions thereof, polynucleotides encoding the heavy and/or light chain regions of the antibodies, or antigen-binding portions thereof, and vectors comprising the polynucleotides encoding the heavy and/or light chain regions of the antibodies, or antigen-binding portions thereof.
