AHMAD Saleem,TEBBEN Andrew J,GONG Hua,LIU Qingjie,NGU Khehyong,WATTERSON Scott Hunter
申请号:
SI201531306
公开号:
SI3461821T1
申请日:
2015.10.23
申请国别(地区):
SI
年份:
2020
代理人:
摘要:
Disclosed are compounds of Formula (I): or a salt thereof, wherein: X is CR 4 or N; R 1 , R 2 , R 3 , R 4 , and A are defined herein. Also disclosed are methods of using such compounds as inhibitors of Bruton's tyrosine kinase (Btk), and pharmaceutical compositions comprising such compounds. These compounds are useful in treating, preventing, or slowing the progression of diseases or disorders in a variety of therapeutic areas, such as autoimmune diseases and vascular disease.