Jose Mercado,Eric J. Tarcha,Jeffrey J. Posakony,Shawn Iadonato
申请号：
US16734151
公开号：
US20200237924A1
申请日:
2020.01.03
申请国别(地区):
US
年份:
2020
代理人:
摘要：
Provided herein are alpha-conotoxin peptide analogs, including alpha-conotoxin peptide analogs that are covalently attached to polyethylene glycol (PEG), and pharmaceutical compositions of such alpha-conotoxin peptide analogs. Also provided herein are methods of treating or preventing a condition conducive to treatment or prevention by inhibition of an α9-containing nicotinic acetylcholine receptor (nAChR) (e.g., the α9α10 subtype of the nAChR) in a subject.
