A cold and heat exchange system for a cardiac surgical operation with cardiac arrest, comprising: an ice water tank (15), a primary circulation water tank (11), and a secondary circulation water tank (16). Side walls of the primary circulation water tank (11) and the secondary circulation water tank (16) are each provided with an overflow orifice. Each overflow orifice is connected to the ice water tank (15) through a circulation pipe (14). A first roller pump (12) is mounted on a first hose (13). A second roller pump (18) is mounted on a second hose (17). Water in the ice water tank (15) is pumped into the primary circulation water tank (11) and the secondary circulation water tank (16) through the first hose (13) and the second hose (17), respectively. The primary circulation water tank (11) is mounted on a first loop (5) and a second loop (6). The secondary circulation water tank (16) is mounted on a third loop (1). A conventional cold and heat exchange water tank serving as a refrigerating device (compressor) is transformed into an ice water sink 15 so that the cold source is high in safety and low in cost. All parts, in contact with water, of the ice water tank (15), the primary circulation water tank (11), the secondary circulation water tank (16), and conduits of the first to third loops (5, 6, 1) become disposable medical articles, so that breeding of bacteria is fundamentally avoided.