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Methods for designing and preparing vaccines comprising directed sequence polymer compositions via the directed expansion of epitopes
专利权人:
Inc.;Peptimmune
发明人:
Mathers, Thomas,Zanelli, Eric,Bonnin, Dustan,Krieger, Jeff
申请号:
AU2008311897
公开号:
AU2008311897B2
申请日:
2008.10.16
申请国别(地区):
AU
年份:
2015
代理人:
摘要:
The instant invention comprises a process of preparing a composition comprisingdirected sequence polymer (DSP) mixtures that act as epitopes and useful as vaccines,such DSP synthesized according to a set of rules regarding the identity and thefrequency of occurrence of amino acids that substitute a base or native aminoacid of a known epitope. The resulting composition is a mixture of related peptidesfor therapeutic use as a vaccine, preferably for infectious agents that are immuneevasive.
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